نتایج جستجو برای: conserved regions

تعداد نتایج: 433790  

2012
Martin Hemberg Jesse M. Gray Nicole Cloonan Scott Kuersten Sean Grimmond Michael E. Greenberg Gabriel Kreiman

More than 98% of a typical vertebrate genome does not code for proteins. Although non-coding regions are sprinkled with short (<200 bp) islands of evolutionarily conserved sequences, the function of most of these unannotated conserved islands remains unknown. One possibility is that unannotated conserved islands could encode non-coding RNAs (ncRNAs); alternatively, unannotated conserved islands...

Behrokh Farahmand , Mansoureh Tabatabaeian , Masoumeh Tavassoti-Kheiri , Rasoul Soleimani-Stiar , Reza Saghiri , SHima Fattahi, Yasin Panahi ,

Background and Aims: Influenza virus nucleoprotein (NP) has the capacity to be used as subunit vaccine, but little is known about the impact of different cultures on its structure. In the present study we aimed to evaluate and compare the Isoelectric focusing (IEF) property of extracted viral nucleoproteins derived from Madin Darby canine kidney (MDCK) cell line and embryonated chicken eggs (EC...

2015
Chi-Hua Chen Qian Peng Andrew J. Schork Min-Tzu Lo Chun-Chieh Fan Yunpeng Wang Rahul S. Desikan Francesco Bettella Donald J. Hagler Connor McCabe Linda Chang Natacha Akshoomoff Erik Newman Thomas Ernst Peter Van Zijl Joshua Kuperman Sarah Murray Cinnamon Bloss Mark Appelbaum Anthony Gamst Wesley Thompson Hauke Bartsch Michael Weiner Paul Aisen Ronald Petersen Clifford R. Jack Jr William Jagust John Q. Trojanowki Arthur W. Toga Laurel Beckett Robert C. Green Andrew J. Saykin John Morris Leslie M. Shaw Zaven Khachaturian Greg Sorensen Maria Carrillo Lew Kuller Marc Raichle Steven Paul Peter Davies Howard Fillit Franz Hefti Davie Holtzman M. Marcel Mesulman William Potter Peter J. Snyder Adam Schwartz Tom Montine Ronald G. Thomas Michael Donohue Sarah Walter Devon Gessert Tamie Sather Gus Jiminez Danielle Harvey Matthew Bernstein Nick Fox Paul Thompson Norbert Schuff Charles DeCarli Bret Borowski Jeff Gunter Matt Senjem Prashanthi Vemuri David Jones Kejal Kantarci Chad Ward Robert A. Koeppe Norm Foster Eric M. Reiman Kewei Chen Chet Mathis Susan Landau Nigel J. Cairns Erin Householder Lisa Taylor-Reinwald Virginia M.Y. Lee Magdalena Korecka Michal Figurski Karen Crawford Scott Neu Tatiana M. Foroud Steven Potkin Li Shen Kelley Faber Sungeun Kim Kwangsik Nho Leon Thal Richard Frank Neil Buckholtz Marilyn Albert John Hsiao Lars T. Westlye William S. Kremen Terry L. Jernigan Stephanie Le Hellard Vidar M. Steen Thomas Espeseth Matt Huentelman Asta K. Håberg Ingrid Agartz Srdjan Djurovic Ole A. Andreassen Nicholas Schork Anders M. Dale

Little is known about how genetic variation contributes to neuroanatomical variability, and whether particular genomic regions comprising genes or evolutionarily conserved elements are enriched for effects that influence brain morphology. Here, we examine brain imaging and single-nucleotide polymorphisms (SNPs) data from ∼2,700 individuals. We show that a substantial proportion of variation in ...

Background: Argas persicus has a great importance for health and veterinary, it can transmit many infectious agents such as Borrelia anserina (avian spirochetosis) and Aegyptianella pullorum. Distinguishing Argasidae due to close morphological relationship is difficult. OBJECTIVES: In the present study, we performed molecular analyses based on PCR and sequencing of Amplicon derived from 16S rRN...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1974
J D Capra J M Kehoe

The variable regions of five human immunoglobulin heavy chains of the V(H)III subgroup have been totally sequenced. Three of the heavy chains belonged to the IgG class and two to the IgA class. Examination of these sequences, and comparison with additional published heavy chain sequences, showed that a total of four hypervariable regions is characteristic of human heavy chain variable regions. ...

Degenerate primers-based polymerase chain reaction (PCR) are commonly used for isolation of unidentified gene sequences in related organisms. For designing the degenerate primers, we propose the use of local alignment search method for searching the conserved regions long enough to design an acceptable primer pair. To test this method, a WD40 repeat-containing domain protein from Beauveria bass...

Journal: :progress in biological sciences 2013
ahmad-reza katouzian hassan rajabi-maham

the identification of the efficiency of some mtdna genes of mus musculus species complex (house mouse) for biosystematics research was studied in this approach. recent studies have made use of different mitochondrial genes including nadh dehydrogenase genes, cytochrome b gene, cytochrome oxidase genes, d-loop region and whole mtdna genome to study the house mouse species. usage of each of these...

Journal: :iranian journal of animal biosystematics 0
s. abdollahi h. fathpour k. aghaei pour

ticks are an important problem among zoonotic diseases. main veterinary species of hard ticks are: hyalomma sp. boophilus sp and rhipicephalus sp. among them hyalomma sp. have widespread distribution in iran and middle east. the best method to control hyalomma sp. is immunological one, by using antigens, which causes immunologic and physiologic reactions in host.bm86 is one of the best antigens...

Journal: :Genome research 2002
Anil G Jegga Shawn P Sherwood James W Carman Andrew T Pinski Jerry L Phillips John P Pestian Bruce J Aronow

Evolutionarily conserved noncoding genomic sequences represent a potentially rich source for the discovery of gene regulatory regions. However, detecting and visualizing compositionally similar cis-element clusters in the context of conserved sequences is challenging. We have explored potential solutions and developed an algorithm and visualization method that combines the results of conserved ...

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