OBJECTIVE To study the performance of pharmacogenetics-based warfarin dosing algorithms in the initial and the stable warfarin treatment phases in a cohort of Han-Chinese patients undertaking mechanic heart valve replacement. METHODS We searched PubMed, Chinese National Knowledge Infrastructure and Wanfang databases for selecting pharmacogenetics-based warfarin dosing models. Patients with me...

This interactive session presents early research findings resulting from a game simulation currently called Gamestar Mechanic through which 70 middle and high school-age players learn to design video games. Gamestar Mechanic is an RPG (Role-Playing Game) style online game through which players “take on” the behaviors characteristic of professional game designers (e.g., designing games, accounti...

This paper presents a class of theoretical and iterative method for linear partial differential equations. An algorithm and analytical solution with a initial condition is obtained using the reduced differential transform method. In this technique, the solution is calculated in the form of a series with easily computable components. There test modeling problems from mathematical mechanic, physi...

This paper explores the pedagogical potential of Gamestar Mechanic, a computer game where players learn the principles of game design by making, sharing and reviewing games in the context of an online community of designers. The game has been designed to foster the appropriation of complex language and literacy skills by middle school children. By relying on think aloud interviews and a discour...