Studies have demonstrated a relationship between mammographic texture and breast cancer risk. To date, texture analysis has been limited by tissue superimposition in mammography. Digital Breast Tomosynthesis (DBT) is a novel x-ray imaging modality in which 3D images of the breast are reconstructed from a limited number of source projections. Tomosynthesis alleviates the effect of tissue superim...

We have explored the vascular response of the breast to inspiration of Carbogen. Results show greater changes in vasoconstriction and HbSat in the tumor-bearing breast compared to the healthy contralateral breast of the same patient. OCIS codes: (170.3830) Mammography; (170.1610) Clinical applications

Granular cell tumor (GCT) is a benign tumor of the breast that can mimic, on breast imaging, invasive carcinomas. Biological evolution of mammary GCT is unknown, especially if it is associated with an invasive carcinoma in the same or contralateral breast. This report details the morphological features of these synchronous lesions highlighting their biological characteristics and suggesting an ...

Rhabdomyosarcoma rarely metastasizes to the breast. We report a case of a pediatric patient who initially presented with a right breast mass and pancytopenia, which was subsequently diagnosed as alveolar rhabdomyosarcoma. Despite initial favorable response to chemotherapy, a new metastatic focus was found in the contralateral breast 10 months later.

BACKGROUND Radiotherapy is an important treatment of choice for breast cancer patients after breast- conserving surgery, and we compare the feasibility of using dual arc volumetric modulated arc therapy (VMAT2), single arc volumetric modulated arc therapy (VMAT1) and Multi-beam Intensity Modulated Radiotherapy (M-IMRT) on patients after breast-conserving surgery. MATERIALS AND METHODS Thirty ...

KEY CLINICAL MESSAGE The patient developed multiple bone metastases following mastectomy with silicone reconstruction and contralateral augmentation for ductal carcinoma in situ (DCIS) of the breast. She was diagnosed with contralateral invasive cancer. Distant metastasis of DCIS is rare, and other metastatic origins must be screened. However, screening of augmented breasts is difficult.

BACKGROUND The aim of the study was to compare the two irradiation modes with (FF) and without flattening filter (FFF) for three different treatment techniques for simultaneous integrated boost radiation therapy of patients with right sided breast cancer. METHODS An Elekta Synergy linac with Agility collimating device is used to simulate the treatment of 10 patients. Six plans were generated ...

PURPOSE To quantify the potential advantages of prone position breast radiotherapy in terms of the radiation exposure to out-of-field organs, particularly, the breast or the lung. Several dosimetric studies have been reported, based on commercial treatment planning software (TPS). These TPS approaches are not, however, adequate for characterizing out-of-field doses. In this work, relevant out-o...