Copyright © 2006 Massachusetts Medical Society. A 71-year-old man with type 2 diabetes and hypertension is referred for coronary angiography. His medications include metformin and a thiazide. Before the angiogram, his serum creatinine level is 1.8 mg per deciliter (160 μmol per liter), yielding an estimated glomerular filtration rate of 40 ml per minute per 1.73 m2 of body-surface area. What ca...

Contrast-induced acute kidney injury (CI-AKI), or nephropathy (CIN), is frequently diagnosed in the setting of coronary angiography. The incidence varies in the literature partly related to the differences in diagnostic criteria used for CIN. In a recently published article in Circulation, Maioli et al1 used a definition of an increase of 0.5 mg/dL over baseline serum creatinine within 3 days o...

Copyright © 2006 Massachusetts Medical Society. A 71-year-old man with type 2 diabetes and hypertension is referred for coronary angiography. His medications include metformin and a thiazide. Before the angiogram, his serum creatinine level is 1.8 mg per deciliter (160 μmol per liter), yielding an estimated glomerular filtration rate of 40 ml per minute per 1.73 m2 of body-surface area. What ca...

The administration of iodinated contrast media (CM) is a standard component of many computed tomography (CT) examinations. The large number of procedures performed each year and the infrequency of adverse events attests to the safety of CM. However, a small number of patients experience adverse events that are directly related to the CM or the procedure being performed. In this chapter, we exam...

CONTEXT Contrast-induced nephropathy (CIN) is a common cause of acute kidney dysfunction. EVIDENCE ACQUISITIONS Directory of Open Access Journals, Google Scholar, PubMed, EBSCO and Web of Science have been searched. RESULTS It is necessary to identify at risk patients at early stages to implement preventive strategies to decrease the incidence of this nephropathy. However, mechanisms of CIN...

Contrast-induced nephropathy (CIN) is a serious, but potentially preventable adverse event associated with the use of iodinated contrast media (CM). Studies suggest that the occurrence of CIN is directly related to the number of pre-existing patient risk factors such as pre-existing renal insufficiency (RI) with or without diabetes, advanced age, congestive heart failure and dehydration. Becaus...

Contrast media induced nephropathy (CIN) leading to acute renal failure is a rare event associated with iodinated contrast agents. Several studies published recently in Radiology (1-3) suggest the risk of contrast induced nephropathy (CIN) following intravenous iodinated contrast administration is much lower than previously believed. In this article we provide an update on recent revisions to o...

An increasing number of diagnostic imaging and interventional procedures require the use of radiographic contrast agents which has led to a parallel increase in the incidence of contrast-induced nephropathy (CIN). CIN is a serious clinical problem associated with increased morbidity and mortality, particularly in patients with chronic renal failure (see the Case Report). A key step to minimize ...

Cancer patients undergo frequent imaging examinations. Computed tomography (CT) examinations for tumor staging and assessment of treatment response generally require administration of intravascular contrast medium. Iodinated contrast agents for CT are associated with the risk of contrast-induced nephrotoxicity (CIN), particularly in patients with impaired renal function and diabetes. In many ca...

background: carotid artery stenting is now used as an alternative to surgical endarterectomy. this study was done to assess the feasibility, safety, and immediate and late clinical outcomes in patients undergoing carotid stenting . methods: between july 2008 and december 2009, a total of 40 patients (20 male, mean age: 65 ± 11 years, 19 symptomatic, and 90% high risk for endarterectomy) underwe...