A pillar[6]arene-based supramolecular amphiphile has been constructed in water. The supramolecular amphiphile formed vesicles, which could be regulated by pH, light and enzymes, and thus the loaded dye in the vesicles could be released in a controlled manner.

Chemical imaging with sufficient spatial resolution to resolve microparticles in tablets is essential to ensure high quality and efficacy in controlled release. The existing modalities have the following disadvantages: they are time-consuming or have poor spatial resolution or low chemical specificity. Here, we demonstrate an epi-detected mid-infrared photothermal (epi-MIP) microscope at a spat...

Exploiting binding affinities between molecules is an established practice in many fields, including biochemical separations, diagnostics, and drug development; however, using these affinities to control biomolecule release is a more recent strategy. Affinity-controlled release takes advantage of the reversible nature of noncovalent interactions between a therapeutic protein and a binding partn...

We report experimental evidence that light storage, understood as the controlled release of a light pulse by an atomic sample dependent on the past presence of a writing pulse, is not restricted to small-group-velocity media but can also occur in a negative-group-velocity medium. We present a numerical modeling in close agreement with our observations and a simple physical picture applicable to...

Here we report a new peptide modified mesoporous silica nanocontainer (PMSN) as a novel controlled release system. The peptides are part of a stimuli responsive nanovalve and ensure an efficient cellular uptake.

The purpose of writing this review on gastroretentive drug delivery systems was to compile the recent literature with special focus on various gastroretentive approaches that have recently become leading methodologies in the field of site-specific orally administered controlled release drug delivery. In order to understand various physiological difficulties to achieve gastric retention, we have...

We present the fabrication of nanoscale electroactive thin films that can be engineered to undergo remotely controlled dissolution in the presence of a small applied voltage (+1.25 V) to release precise quantities of chemical agents. These films, which are assembled by using a nontoxic, FDA-approved, electroactive material known as Prussian Blue, are stable enough to release a fraction of their...

Cucurbit[6]uril-based reversible bistable [2]pseudorotaxanes were designed, synthesized and installed on the surface of mesoporous silica nanoparticles as supramolecular nanovalves. The assembled mechanized silica nanoparticles realize the multistage pH-controlled release of benzotriazole and the potential for reutilization.

In a new concept, an iodine loaded amine functionalized MOF was employed as a syringe pump for the slow release of iodine as a catalyst in the synthesis of thienyl dipyrromethanes under ambient conditions and turned out to be successful. The catalytic activities were compared with an isoreticular non-functionalized MOF and other conventional catalysts.