Tipping points--where systems shift radically and potentially irreversibly into a different state--have received considerable attention in ecology. Although there is convincing evidence that human drivers can cause regime shifts at local and regional scales, the increasingly invoked concept of planetary scale tipping points in the terrestrial biosphere remains unconfirmed. By evaluating potenti...

This paper examines the issue of state contingency in interest rate linkages across the G7 economies by employing Kalman (1960,1963) filter techniques to estimate time varying parameter models of bilateral dependence. Our results show that there is convincing evidence that international linkages in interest rates vary considerably over time. There are periods when international interest rate mo...

The information extraction system iDocument interactively extracts information from text such as instances and relations with respect to existing background knowledge. An extraction process creates weighted recommendations describing indications of relevant information. During execution, each process step records its output into an instantiated process model. We reused these bits of information...

Many decades of research have produced a significant amount of data showing increased oxidative stress in asthma and indicating a potential role for oxidants in the pathogenesis of the disease, particularly during exacerbations. Putatively relevant pro-oxidative mechanisms have also been identified. Currently available asthma drugs are generally effective for the treatment of the disease, but t...