Epilepsy is a disorder of the central nervous system characterized by periodic loss of consciousness with or without convulsions associated with abnormal electrical activity in the brain. In some cases it is due to brain damage, but in most cases the cause is unknown. Epilepsy is a common, sometimes chronic, neurological condition with physical risks and psychological and socioeconomic conseque...

OBJECTIVE To investigate the excess mortality due to remote symptomatic epilepsy, taking account of frequency and type of seizures. METHODS The authors compared mortality in persons with (n = 8,156) and without (n = 72,526) history of epilepsy in a 1988 to 1999 California population of persons with mild developmental disabilities. Subjects had traumatic brain injury, cerebral palsy, Down synd...

Psychogenic non-epileptic seizures (PNES) in the context of meningoencephalitis can occur with sufficient stressors. Video-EEG is a critical diagnostic tool in such complex cases. Once the diagnosis of PNES is confirmed by video-EEG, psychiatric consultation with psychotherapeutic intervention to address underlying psychopathology and specific stressors that led to these conversion symptoms is ...

OBJECTIVE Febrile seizure (FS) is the most common form of childhood seizure disorders. FS is perhaps one of the most frequent causes of admittance to pediatric emergency wards worldwide. We aimed to identify a new, safe, and effective therapy for preventing FS recurrence. METHODS A total of 115 children with a history of two or more episodes of FS were randomly assigned to levetiracetam (LEV)...

Openchowski2 first observed that dogs developed generalized convulsions some hours after a small portion of their cerebral cortices had been frozen. Speransky' confirmed and extended this observation and noted that the administration of morphine greatly increased both the incidence and severity of the convulsions. He also pointed out the striking resemblance of these disturbances in the dog to ...

normal 0 false false false en-us x-none ar-sa epilepsy is more common in patients with multiple sclerosis (ms) than in the general population, occurring in 2%–3% of patients. convulsions may be either tonic–clonic in nature or partial complex. in these individuals, seizures most likely result from lesions present in the cerebral cortex and subcortical white matter. a jacksonian seizure is a typ...

OBJECTIVE Seizures continue to be a major problem in the pediatric age group. The cause and clinical presentation of these seizures are vast and variable. This is a prospective study, conducted with the aim of assessing the magnitude and presentation of this problem in the region of Al-Madina Al-Munawara, Kingdom of Saudi Arabia. METHODS All the cases of seizures admitted to Madina Maternity ...

Efforts in basic neuroscience and studies of rare hereditary neurological diseases are partly motivated by the hope that such work can lead to better understanding of and treatments for the common neurological disorders. An example is the progress that has resulted from identification of the genes that cause benign familial neonatal convulsions (BFNCs). Benign familial neonatal convulsions is a...