Hypothyroidism from iodide transport deficiency is a rare disease, especially when found in two affected siblings. Treatment with high doses of iodide has been recommended, but no long term results have been reported. Two siblings with congenital hypothyroidism due to total failure to transport iodide have been followed up during twelve and a half years of treatment with oral potassium iodide. ...

A method for determining the concentration of iodide in beer using high-performance liquid chromatography/electrochemical detection was developed. Simple sample pretreatment of beer was performed using a monolithic silica disk-packed spin column, with a recovery rate of 84.9%. Separation of iodide ions from other endogenous compounds was carried out using a mobile phase of 10 mM sodium phosphat...

It is possible that there is an association between the butanol-insoluble protein-bound iodine developed in plasma when potassium iodide is fed and the reduction of serum and hepatic cholesterol. This fraction constitutes most of the protein-bound iodine increase observed in iodide-fed rabbits, dogs, rats and hypertensive human beings. It appears a few days after iodide feeding is begun and dis...

A procedure for the determination of iodide, thiocyanate and perchlorate ions in environmental water by two-dimensional ion chromatography has been developed. At first the iodide, thiocyanate and perchlorate ions were separated from interfering ions by a column (IonPac AS16, 250 mm x 4 mm). The iodide ion, thiocyanate and perchlorate ions were then enriched with an enrichment column (MAC-200, 8...

new kinds of hydroquinone derivatives were synthesized and along with a azo dye applied as additives in the iodide/iodine redox electrolyte for dye-sensitized solar cells and their effect on the short-circuit photocurrent of dye sensitized solar cells was investigated. addition of 0.05 m a hydroquinone derivative in the electrolyte comprising 0.5 m 1-methyl-3-propylimidazolium iodide (mpii) and...

McGinty and Sharp (1) demonstrated that the thyroid glands of rats treated with propylthiouracil retained the ability to concentrate iodide ion but failed to bind the iodine in an organic form. VanderLaan and VanderLaan (2) and Stanley and Astwood (3) showed also that thyroidal iodide, "trapped" under the influence of the antithyroid drugs, could be rapidly discharged from the gland by the admi...

Iodide is an important regulator of thyroid activity. Its excess elicits the Wolff-Chaikoff effect, characterized by an acute suppression of thyroid hormone synthesis, which has been ascribed to serum TSH reduction or TGF-beta increase and production of iodolipids in the thyroid. These alterations take hours/days to occur, contrasting with the promptness of Wolff-Chaikoff effect. We investigate...