PURPOSE We describe a case of full-thickness corneal restoration after an acute corneal burn with an acid agent. METHODS A 32-year-old male reported painful discomfort, redness, photophobia, and a decrease in visual acuity in the left eye after a unilateral burn with an acid agent. Slit-lamp examination revealed massive corneal melting involving necrotic sequestrum of the entire corneal surfa...

The cornea of a 64-year-old white male underwent progressive thinning following removal of a foreign body and after treatment with topical antibiotics and corticosteroid. Initial attempts at laboratory identification of an infectious agent were negative. The process progressed to corneal perforation. After a penetrating keratoplaty, histopathological examination of host button tissue showed a f...

Bacterial infections ofthe anterior segment ofthe eye are not a common feature of AIDS but once established these infections may be particularly severe and more likely to cause ulcer and perforation.' Pseudonwmas aeruginosa has been cultured in keratitis, corneal ulcers, and scleritis in HIV infected patients2; nevertheless, nobody has previously reported Pseudomonas conjunctival ulcers in HIV ...

The cornea has unique features that make it a useful model for regenerative medicine studies. It is an avascular, transparent, densely innervated tissue and any pathological changes can be easily detected by slit lamp examination. Corneal sensitivity is provided by the ophthalmic branch of the trigeminal nerve that elicits protective reflexes such as blinking and tearing and exerts trophic supp...

Conductive keratoplasty (CK) was approved by the US Food and Drug Administration in March 2004 for the correction of hyperopia ranging from 0.75 to 3.00 diopters (D) and 0.75 D or less of cylinder in patients older than 40 years. With CK, hyperopic correction is achieved through the use of a nonablative radiofrequency that shrinks corneal stromal collagen and steepens the central cornea. A kera...

PURPOSE To report a case of fungal keratitis caused by Metarhizium anisopliae complex. METHODS Case report. RESULTS Our patient presented with a central corneal infiltrate. Fungal culture yielded a Metarhizium species. She was started on antifungal agents with no significant improvement. A therapeutic corneal transplant was performed after perforation. At two years follow up, she was free o...

Early diagnosis offungal keratitis is difficult, and it has been generally associated with poor visual prognosis. We treated a man who had keratomycosis with corneal perforation and lens prolapse caused by Paecilomyces sp, which rarely causes ocular infection. The patient was given antifungal agents, a temporary conjunctival flap, and penetrating keratoplasty. His visual outcome was successful.

A 5-month-old boy with bilateral sclero-cornea, multiple systemic abnormalities, and normal karyotype had his left eye removed after corneal perforation. Histopathological examination of the enucleated eye revealed an irregular corneal epithelium, absent Bowman's membrane, thickened and vascularized stromal lamellae, absent Descemet's membrane and endothelium, no angle structures, hypoplasia of...