PURPOSE Neurotrophic keratopathy (NK) is a corneal degeneration associated with corneal nerve dysfunction. It can cause corneal epithelial defects, stromal thinning, and perforation. However, it is not clear if and to which extent epithelial stem cells are affected in NK. The purpose of this study was to identify the relationship between corneolimbal epithelial progenitor/stem cells and sensory...

Three cases who underwent surgery in different areas of the craniofacial region were reported with bradycardia developing intraoperatively during flap traction. Many cases of the oculocardiac reflex during treatment of the orbital region have been reported in the literature. This manuscript recorded that reflex bradycardia can occur during traction or stretching of any structure innervated...

PURPOSE To compare the visual acuity outcomes between 2 target locations for corneal inlay implantation with concurrent laser in situ keratomileusis (LASIK) to compensate for presbyopia. SETTING Shinagawa LASIK Center, Tokyo, Japan. DESIGN Retrospective cohort study. METHODS Bilateral LASIK was performed simultaneously with inlay implantation in the nondominant eye. The preoperative and 6...

Background: The effect of corticosteroid therapy on corneal wound healing is controversial. The objective of this study was to evaluate the effects of combination therapy with dexametha-sone and acetylcysteine at different times and durations on experimentally-induced corneal wounds and haze in rabbits. Methods: Eighteen adult New Zealand white rabbits were divided into three groups of ...

PURPOSE To measure the increase in tear secretion evoked by selective stimulation of the different populations of sensory receptors of the cornea and conjunctiva by using moderate and intense mechanical, chemical, and cold stimuli. METHODS Six healthy subjects participated in the study. Tear secretion was measured in both eyes by the Schirmer's test conducted under control conditions and afte...

PURPOSE To investigate the accuracy of ocular misalignment measurement, using corneal reflections. METHODS Corneal reflex positions were measured relative to two landmarks, the limbus center and the entrance pupil center, using high-resolution digital images for cyclopean gaze angles from 0 degree to 18.8 degrees (34.04 prism diopters; PD) to the right and to the left in 10 subjects. Distance...

Introduction Patients with mitochondrial myopathies, of which chronic progressive external ophthalmoplegia (CPEO) is the most common, can present with ptosis and proximal limb weakness.1 Ptosis associated with CPEO can provide challenging management problems. This form of ptosis may have poor levator function. Additional features must be considered in determining the surgical treatment. For exa...

OBJECTIVES To assess which signs and symptoms were relieved by gold weight implantation and which signs and symptoms persisted. DESIGN Prospective observational cohort. SETTING Tertiary care neurotology and oncology center. PATIENTS Sixteen (4 males and 12 females) consecutive patients whose average age was 56 years (age range, 31-76 years). Inclusion criteria were gold weight implant, la...