A 70-year-old female developed a bacterial ulcer in a previously rejected corneal graft. Cultures identified the pathogen as Enterobacter cloacae. Intensive topical antibiotic therapy arrested the progress of the ulcer, and the epithelial defect healed in one week; there was no resultant stromal thinning. Factors which may have predisposed the cornea to ulceration by this organism of relatively...

MULES (1894) wrote that where " the action of micro-organisms on an abraded surface may cause or is causing destructive changes " the indications would be to remove the irritating elements and allow the natural process of repair to heal the breach of surface ". He sought to achieve this by placing a gelatine wafer impregnated with iodoform on the corneal surface and keeping the eye bandaged. He...

OBJECTIVE To investigate the efficacy of topical 0.2% hyaluronic acid in canine corneal ulcers in vivo. PROCEDURES Six purpose-bred beagles were randomly assigned into two groups (three dogs/group): group A received experimental product (Optimend™ , containing 0.2% hyaluronic acid, KineticVet™ ); group B received control product (Optimend™ without 0.2% hyaluronic acid and supplemented with ca...

Objective: Corneal grafts have a major risk of fungal keratitis due to long-term local and sometimes systemic steroid/antibiotic use. The aim of this study was to evaluate the efficacy of intrastromal voriconazole as a therapeutic adjunctive for the management of fungal keratitis in corneal graft. Design: Presentation of two cases of fungal keratitis occurring after corneal transplantation and ...

Conjunctival ulceration accompanied with secretion and pain was observed in a 30-year-old male, 3 days after a perforating corneal trauma. Cultures of conjunctival ulcer samples grew Fonsecaea pedrosoi, a major causative agent of chromoblastomycosis that is typically transmitted during trauma. The conjunctival ulcer was successfully treated with amphotericin B, itraconazole, and fluconazole. Th...

ORBITAL DECOMPRESSION P. R. R. CLARKE (Middlesbrough) discussed a series of 20 patients with endocrine exophthalmos treated by lateral orbital decompression. There had been 14 bilateral decompressions, and in six patients a unilateral operation only had been performed. One patient had needed reoperation. Four patients had no thyroid abnormality, and two had untreated hyperthyroidism. In 14 pati...

The authors describe a case of fungal keratitis that the in vivo confocal microscopy helped in the diagnosis and follow-up. Confocal microscopy was done in a patient's ulcer that did not improve with several topical medicines. Corneal scrapings were obtained and culture results were without conclusion. We observed hyphae and infectious collections on confocal microscopy. New corneal culture sho...