INTRODUCTION AND OBJECTIVES Risk stratification in non-ST-elevation acute coronary syndrome makes use of clinical variables that can identify patients at an increased risk of complications. Our objective was to identify clinical variables that predict significant stenosis (i.e., >50%) of the left main coronary artery in high-risk patients who have had a first episode of non-ST-elevation acute c...

background: the t allele of the hepatic lipase (hl) c-514t polymorphism was previously found to be associated with lower plasma hl activity. here, we examined the association between this polymorphism and plasma hdl-cholesterol concentrations in patients with coronary arteries stenosis. methods: we studied 342 subjects undergoing coronary angiography in two groups of non cad (n=146) and cad (n=...

N-Terminal ProANP, and Brain Natriuretic Peptide Affected by the Presence of Coronary Artery Disease? To the Editor: We read with great interest the recent article by BibbinsDomingo et al1 on plasma brain natriuretic peptide (BNP) in outpatients with stable coronary disease. They concluded that elevated levels of BNP are independently associated with inducible ischemia in outpatients with stabl...

OBJECTIVES We aimed to evaluate the ability of vasodilator myocardial contrast echocardiography (MCE) to detect significant infarct-related artery (IRA) stenosis and multivessel disease (MVD) after thrombolysis. BACKGROUND The detection of residual IRA stenosis subtending significant viable myocardium and the identification of MVD may help to triage patients who may benefit from mechanical re...

Intimal hyperplasia, an aberrant proliferation of smooth muscle cells that causes stenosis and graft occlusion, is the primary cause failure grafts after a few years. In this way, using constructal design method, study looks at how degree, junction angle, diameter ratio affect flow through bypass goes around idealised coronary artery partially blocked. The results show effect by several factors...

OBJECTIVE Because of beam-hardening and blooming artifacts, it is difficult to determine the degree of stenosis caused by calcified coronary artery plaques at coronary CT angiography (CTA). Our goal was to determine how accurate coronary CTA is in evaluating these lesions. MATERIALS AND METHODS Thirty-one patients who had one or more calcified coronary artery plaques at coronary CTA underwent...

Background: Cardiovascular diseases are the most common causes of death in the world and type 2 diabetes is one of them because it is highly prevalent and doubles heart disease risk. Some studies suggest that insulin resistance is associated with coronary artery disease in non-diabetics. The aim of this study was to evaluate the association of insulin resistance (IR) and coronary artery disease...

OBJECTIVE Fibroblast growth factor 23 (FGF23) is a circulating regulator of phosphate and vitamin D metabolism and is associated with coronary artery calcification, and has been implicated in the pathogenesis of cardiovascular disease. The aim of this study was to determine whether circulating FGF23 concentration is independently associated with the severity and extent of coronary artery diseas...

cardiovascular diseases are one of the most common diseases that cause a large number of deaths each year. coronary artery disease (cad) is the most common type of these diseases worldwide and is the main reason of heart attacks. thus early diagnosis of cad is very essential and is an important field of medical studies. many methods are used to diagnose cad so far. these methods reduce cost and...