c t a A 74-year-old man, with a history of heavy smoking, presented with unstable angina (Figure 1). Dobutamine stress echocardiography showed ischemia in the right coronary artery territory. Coronary angiography revealed no obstructive epicardial disease in the left dominant circulation (Figure 2A); the right coronary artery (RCA) was a small caliber and tortuous vessel, with only minor athero...

The article presents a historical review. For several decades, the diseases of circulatory system have remained one most pressing problems mankind. However, in recent years there has been tendency to decrease mortality from cardiovascular pathologies including coronary heart disease. At dawn study artery disease, problem surgical treatment pathology looked practically unsolvable: was no knowled...

Background There is growing evidence for a pathogenic role for cytokines in atherogenesis. The presence of certain cytokines has been documented in human atherosclerotic vessels. This study was designed to investigate cytokine production by mononuclear leukocytes from patients with ischemic heart disease. Methods and Results We measured kinetics of secretion of tumor necrosis factor-a (TNF-a) a...

INTRODUCTION The incidence of ischemic heart disease is higher in patients with HIV/AIDS. However, the frequency of angina pectoris in these patients is still not known. Literature about this subject is still scarce. OBJECTIVE To evaluate the prevalence of angina pectoris and risk factors for coronary disease and to examine the association between traditional risk factors and HIV-related risk...

    Abstract   Despite sophisticated conventional medical treatment and the continued development   and improvement of coronary revascularization modalities in recent years, a significant   number of patients still suffer from refractory angina pectoris and cannot be successfully   managed. Advances in therapeutic options have led to an increase in the average of life   expectancy even in such ...

Inhalation of cold air (-20°C) for four minutes provoked angina pectoris in four of 17 coronary disease patients at rest and in four of seven of the patients while they were paced at a heart rate level which was subanginal at room temperature. The cold air did not increase myocardial 02 consumption significantly, and the accompanying changes in systemic hemodynamic factors known to influence my...

SEVERE or intractable chest pain, associated with sweating, vomiting, precipitate fall of arterial blood pressure, fever, and evidence of shock or collapse, clearly indicates a diagnosis of acute myocardial infaretion. In marked contrast is the entity of angina pectoris, with its paroxysms of chest pain after effort, typical radiation of pain into the arm, feeling of viselike constriction in th...

SEVERE or intractable chest pain, associated with sweating, vomiting, precipitate fall of arterial blood pressure, fever, and evidence of shock or collapse, clearly indicates a diagnosis of acute myocardial infaretion. In marked contrast is the entity of angina pectoris, with its paroxysms of chest pain after effort, typical radiation of pain into the arm, feeling of viselike constriction in th...

Spontaneous coronary artery dissection is a rare cause of acute coronary syndrome. Spontaneous coronary artery dissection can cause stable angina pectoris, unstable angina pectoris, acute myocardial infarction, cardiogenic shock and sudden cardiac death. It usually occurs in young to middle aged women. Atherosclerosis, peripartum period, and structural and inflammatory diseases affecting the ar...

BACKGROUND The objective of this study is to test the effect of permanent right internal mammary artery device closure on coronary collateral function and myocardial ischemia. METHODS AND RESULTS This was a prospective, open-label clinical trial in 50 patients with coronary artery disease. The primary study end point was coronary collateral flow index as obtained during a 1-minute proximal ri...