there have been a number of developments in screw design and implantation techniques over recent years, including proposal of an alternative trajectory entitled as cortical bone trajectory (cbt). cortical bone trajectory has been investigated in recent medical treatments as an alternative for screw fixation aimed at increasing purchase of pedicle screws in higher density bone. cbt screw inserti...

AIM This study aimed to report a well-succeeded use of equine enzyme-deantigenic cortical membrane and bone granules for guided bone regeneration (GBR) in the esthetic zone concomitant with implant placement. BACKGROUND In the anterior maxilla, where patients typically have the highest expectations for implant-supported restorations, bone resorption in the wake of tooth loss often leads to a ...

The objective of this study was to more fully understand the mechanical behavior of bone tissue that is important to find an alternative material to be used as an implant and to develop an accurate model to predict the fracture of the bone. Predicting and preventing bone failure is an important area in orthopaedics. In this paper, the macrodamage accumulation models in the bone tissue have been...

Introduction: Trabecular bone adapts to external loading conditions in terms of mass and trabecular orientation. Mature trabecular bone is subject to continuous tissue remodeling by BMU’s of osteoblasts and osteoclasts, active mainly at the trabecular surfaces. The regulatory mechanisms that control osteoclast and osteoblast activities in bone modeling (growth or adaptation) and in remodeling (...

There is growing evidence that insulin-like growth factor 1 (IGF-1) and parathyroid hormone (PTH) have synergistic actions on bone and that part of the anabolic effects of PTH is mediated by local production of IGF-1. In this study we analyzed the skeletal response to PTH in mouse models with manipulated endocrine or autocrine/paracrine IGF-1. We used mice carrying a hepatic IGF-1 transgene (HI...

Aims The increasing interest in cortical bone strenght [1,2] led up to the investigation of the cortical tissue through X-ray microcomputed tomography (microCT). In the past histology has been the gold standard for the morphometric examination of bone specimens but this new method permits the non-destructive analyses of specimens in a faster way preserving the integrity of the samples [3] and t...

objective: at present, growth factor-containing products such as enamel matrix derivatives, recombinant bone morphogenetic protein (rh-bmp), recombinant platelet derived growth factor and platelet rich plasma (prp) have gained increasing attention. prp is an autologous source of platelet growth factors used to enhance healing of soft and hard tissues. prp has gained popularity due to its autolo...

Three-dimensional hierarchical structure of female Sprague-Dawley rat tibia cortical bone was characterized as a function of age (3, 12, 32, 42, 60, and 72 wk) using a high-resolution micro-computed tomography. At the whole bone level, 3-wk samples exhibited statistically significant differences in a mean total tissue volume, mean cortical bone volume, mean cortical bone volume density, mean pe...

OBJECTIVE To determine the concentrations of lead (Pb) and cadmium (Cd) in three kinds of materials (cartilage, cortical bone, and cancellous bone) of the femur head obtained from patients in the process of operation. METHODS Concentrations of Pb and Cd were determined in selected parts of the femur head of 30 patients after total hip arthroplasty, using ICP-AES (atomic absorption spectrophot...

Bone is a highly specialized supporting framework of the body, characterized by its rigidity, hardness, and power of regeneration and repair. It protects the vital organs, provides an environment for marrow (both blood forming and fat storage), acts as a mineral reservoir for calcium homeostasis and a reservoir of growth factors and cytokines, and also takes part in acid–base balance (Taichman ...