Idiopathic bronchiolitis obliterans with organizing pneumonia (BOOP) is a clinicopathologic syndrome characterized by an indolent course and favorable prognosis. This report describes five patients with a ful¬ minating and life-threatening variant of this syndrome. Four patients presented with respiratory failure requir¬ ing respiratory assistance and positive pressure ventila¬ tion. Early reco...

set of CSCR following periocular corticosteroid injection with confirmation by OCT imaging. Periocular corticosteroids may be administered for the treatment of uveitis as well as postoperative CME. The presence of intraocular inflammation secondary to uveitis may affect the retinal pigment epithelial barrier and increase susceptibility to local periocular corticosteroid effects. A similar mecha...

Fibrinous pupillary membranes can develop after intraocular surgery and consist of precipitates of inflammatory cells, pigment and fibrin. Formation of intraocular fibrin following vitrectomy surgery is a potentially serious complication that may lead to surgical failure. They usually can be resolved with topical corticosteroid therapy, but, in some cases, can persist despite aggressive topical...

BACKGROUND Tuberculosis causes approximately 8.6 million disease episodes and 1.3 million deaths worldwide per year. Although curable with standardized treatment, outcomes for some forms of tuberculosis are improved with adjunctive corticosteroid therapy. Whether corticosteroid therapy would be beneficial in treating people with pulmonary tuberculosis is unclear. OBJECTIVES To evaluate whethe...

https://doi.org/10.4068/cmj.2018.54.1.74 C Chonnam Medical Journal, 2018 Chonnam Med J 2018;54:74-75 Corresponding Author: Jong Chun Park Department of Cardiology, Chonnam National University Hospital, 42 Jaebong-ro, Dong-gu, Gwangju 61469, Korea Tel: +82-62-220-6246, Fax: +82-62-223-3105, E-mail: [email protected] Article History: Received November 19, 2017 Revised November 26, 2017 Accepted De...

OBJECTIVE To assess whether corticosteroids, used as adjunctive therapy for pediatric severe sepsis, is associated with improved outcomes. DESIGN Retrospective cohort study examining the clinical database derived from the RESOLVE (REsearching severe Sepsis and Organ dysfunction in children: a gLobal perspective, F1K-MC-EVBP) trial of activated protein C for pediatric severe sepsis. SETTING ...

BACKGROUND AND AIMS Microarray analysis of RNA expression allows gross examination of pathways operative in inflammation. We aimed to determine whether genes expressed in whole blood early following initiation of intravenous corticosteroid treatment can be associated with response. METHODS From a prospectively accrued cohort of 128 pediatric patients hospitalized for intravenous corticosteroi...

Subacromial septic bursitis after corticosteroid injection is exceedingly rare. This report describes a case of Staphylococcus aureus subacromial septic bursitis after corticosteroid injection in a patient undergoing isotretinoin (Accutane) therapy. This case is only the third reported in the literature linking a corticosteroid injection with septic subacromial bursitis and the first to describ...

BACKGROUND Acute interstitial nephritis (AIN) is a recognized cause of reversible acute renal failure characterized by the presence of an interstitial inflammatory cell infiltrate. METHODS In order to evaluate the clinical characteristics and management of this disorder, we performed a retrospective study of all cases of AIN found by reviewing 2598 native renal biopsies received at our instit...