Cortisone and ACTH have been the focus of high hopes and grave fears and the centre 'of heated argument ever since their dramatic effect on rheumatoid arthritis was first announced by Philip Hench of the Mayo Clinic in I949. Because of the suffering caused by rheumatoid arthritis and the long history of frustration and failure to find a cure, they were hailed at first with little critical asses...

In this study we tested the use of salivary cortisol and cortisone as alternatives to serum cortisol. Salivary cortisol is often undetectable and contaminated by hydrocortisone. Salivary cortisone strongly reflects serum cortisol.

Background:  Geographic and doctor-to-doctor variations in care are a focus of quality and safety efforts in medicine. This study addresses factors associated with variation in the rate of operative treatment of de Quervain tendinopathy.   Methods: We used a database including all patient encounters at 2 large medical centers, to study the experience of 10 hand surgeons and 1 physiatrist workin...

THE majority of the reports which have been published on the treatment of syphilitic interstitial keratitis with topical cortisone have been concerned only with the more or less immediate effects of the hormone, and very few cases observed for more than about a year have been included. The reports have been conflicting, some authors obtaining excellent results, and others mediocre or poor resul...