UNLABELLED A high cardiothoracic ratio (CTR) is indicative of a cardiac disorder. However, few reports have revealed an association between the CTR and mortality in patients starting hemodialysis (HD). METHODS Patients with HD initiation (n = 387; mean age, 66.7 ± 12.7 years) were divided into the following three groups according to their CTR at HD initiation: CTR <50%, 50% ≤ CTR < 55%, and C...

Analysis of covariance serves two main purposes in the analysis of clinical trials. It provides for a more powerful statistical test through variance reduction for comparison of treatment groups; and it addresses comparisons between randomized groups with adjustment for random imbalance of covariates. Certain methods of covariance analysis such as logistic regression for ordinal response data a...

OBJECTIVE Secondary cytoreductive surgery (SCS) is reported to be beneficial for patients with recurrent epithelial ovarian carcinoma (EOC). The current study is to evaluate risk factors that would affect the surgical optimal resection rate and prognosis of recurrent EOC after SCS in Chinese patients. METHODS In our study, 44 patients with recurrent EOC treated with SCS at Shandong Cancer Hos...

The possible effect of age, race, sex, consciousness upon admission, geographic location, and history of selected risk factors on the survival after stroke due to infarction or hemorrhage was determined using proportional hazards analysis (Cox regression). For each diagnostic category the most significant prognostic factor was consciousness upon admission. Increasing age, cardiac disease, or pr...

BACKGROUND Prostate cancer (PCa) is very common and frequently metastasizes to the spine. However, PCa spinal metastases were rarely reported in the literature. In this study, the outcome of therapies and prognostic factors affecting surgical outcomes for patients with PCa spinal metastases are discussed to select the best candidates for aggressive surgical resection. METHODS All patients aff...

Since the pioneering work of Thomas and Grunkemeier (1975) and Owen (1988), the empirical likelihood has been developed as a powerful nonparametric inference approach and become popular in statistical literature. There are many applications of empirical likelihood in survival analysis. In this paper, we present an overview of some recent developments of the empirical likelihood for survival dat...

We propose a general framework which can be used for modeling and predicting the popularity of online contents. The aim of our modeling is not inferring the precise popularity value of a content, but inferring the likelihood with which the content will be popular. Our approach is rooted in survival analysis which deals with the survival time until an event of a failure or death. Survival analys...

Objectives The Cox proportional hazards (PH) model is commonly used in randomised clinical trials (RCTs) to assess a treatment effect after adjusting for known prognostic factors. However, the Cox model requires that a covariate effect is constant over time. Violation of this assumption invalidates the simple Cox model. Various PH checks exist, some in the form of statistical tests and some emp...

Materials and methods We conducted prospective cohort study of patients enrolled in care and treatment facilities in Dar es Salaam from October 2004 to September 2011. LTFU was defined as missing clinic visit for 90 and 180 consecutive days after the last scheduled appointment date among patients on ART and care and monitoring respectively. For univariate and multivariate analysis, Cox proporti...

Data extraction: Data were extracted from FDA and sponsor documents and corroborated with published articles when available. Thirty-day survival was assessed by metaanalysis using a fixed-effects model and time-dependent risk by Kaplan-Meier analysis with Cox proportional hazards regression modeling. Where deaths were described within a range of days after treatment, an extreme assumption was m...