Q fever is a zoonotic disease caused by a rickettsia Coxiella burnetii. Since its first description in 1937, the disease has been found to be present in most countries of the world. Serological evidences of Q fever in humans and coxiellosis in animals were reported in Japan in the 1950s, however, systematic studies of the disease did not begin until the report of isolation of C. burnetii from a...

With the use of the complement fixation test, 8,900 cattle were tested for antibodies to Coxiella burnetii. These were randomly selected from 178 different farms in 37 districts in the Transvaal. The percentage of cattle in the sample with positive antibody titres was equal to 7.78%, with a standard error of 0.28%. Because of the large size of the sample, asymptotic normality can be relied upon...

This report reviews the pulmonary and extrapulmonary manifestation of infections due to Coxiella burnetii. Q fever, a zoonosis, is due to infection with C. burnetii. This spore-forming microorganism is a small gram-negative coccobacillus that is an obligate intracellular parasite. The most common animal reservoirs are goats, cattle, sheep, cats, and occasionally dogs. The organism reaches high ...

Coxiella burnetii and Chlamydia trachomatis are bacterial obligate intracellular parasites that occupy distinct vacuolar niches within eucaryotic host cells. We have employed immunofluorescence, cytochemistry, fluorescent vital stains, and fluid-phase markers in conjunction with electron, confocal, and conventional microscopy to characterize the vacuolar environments of these pathogens. The aci...

background: q fever is an important widespread reemerging zoonosis. the presence of coxiella burnetii in 100 tick-infested dogs was assessed in this study. methods: the blood samples from 100 referred dogs were acquired and evaluated by nested-pcr. results: c. burnetii was detected in 11 out of 100 (11%) blood samples. most of the positive dogs were kept outdoor and fed on raw diet. based on ou...

Pleomorphic bacteria are classified in three groups: large cell variants (LCV), small-cell variants (SVC) and small dense cells (SDC). The SCVs and the SDCs are the most frequent forms in the host and certainly (the most) resistant forms in the environment. The LCV form of Coxiella burnetii, which shares features common with gram-negative bacteria, diffuse chromatin and process clearly distingu...

Many animal species, including macropods, have the potential to act as atypical reservoirs of the causative agent of Q fever, Coxiella burnetii. The objective of this study was to determine the seroprevalence of C. burnetii in various macropod species in Australia. Competitive and indirect ELISAs were developed for the testing of macropod sera for antibodies to phase II and I C. burnetii antige...

Although Coxiella burnetii is considered to be an obligate intracellular bacterium and grows in embryonated eggs, laboratory animals and cell culture, recently it has been grown in cell-free media and on agar plates. This current study was conducted to compare four cell lines for their yield of C. burnetii. Four different isolates of C. burnetii (Henzerling, Arandale, Cumberland and Timony) wer...

Coxiella burnetii is the etiologic agent of Q fever, a worldwide distributed zoonosis, accountable for serious health problem both for humans and animals. The exposure to C. burnetii infected animals and their products is the main risk factor for Q fever in humans. Several outbreaks of Q fever have been described in Poland which sources were recognized to be related to imported animals and thei...

Coxiella burnetii is the causative agent of the zoonotic disease Q fever, and ruminants being considered as the main source for human infection. Although the main route of infection in human is inhalation of contaminated aerosols, oral transmission by contaminated raw milk or unpasteurized dairy products is also a possible route of infection. Raw milk or dairy products produced from unpasteuriz...