نتایج جستجو برای: cpe

تعداد نتایج: 1934  

2016
Y Cheng N X Cawley T Yanik S R K Murthy C Liu F Kasikci D Abebe Y P Loh

Patients with Alzheimer's disease (AD), a common dementia among the aging population, often also suffer from depression. This comorbidity is poorly understood. Although most forms of AD are not genetically inherited, we have identified a new human mutation in the carboxypeptidase E (CPE)/neurotrophic factor-α1 (NF-α1) gene from an AD patient that caused memory deficit and depressive-like behavi...

Journal: :Bioscience, biotechnology, and biochemistry 2007
Ah-Jin Kim Yeon-O Kim Jae-Seok Shim Jae-Kwan Hwang

Curcuma xanthorrhiza Roxb., commonly known as Javanese turmeric, has been reported to possess a variety of biological activities, including anti-inflammatory effects, anticarcinogenic effects, wound healing effects, and serum cholesterol-lowering effects. CPE, crude polysaccharide extract isolated from the rhizome of C. xanthorrhiza using 0.1 N NaOH, consisted of arabinose (18.69%), galactose (...

2014
Anugerah Budipratama Adina Fina Aryani Goenadi Franciscus Feby Handoko Dwi Ana Nawangsari Adam Hermawan Riris Istighfari Jenie Edy Meiyanto

New approach of breast cancer therapy is developed toward combination therapy with agents that have a specific molecular target. Our previous study showed that Citrus aurantifolia lime peels ethanolic extract (CPE) increased the sensitivity of MCF-7 cells againts doxorubicin. This study aims to observe the mechanism of combination CPE and doxorubicin in cell cycle modulation and apoptosis on MC...

2013
Alison Suzanne Williams Joel Andrew Mathews David Itiro Kasahara Lucas Chen Allison Patricia Wurmbrand Huiqing Si Stephanie Ann Shore

BACKGROUND Acute ozone (O(3)) exposure results in greater inflammation and airway hyperresponsiveness (AHR) in obese versus lean mice. OBJECTIVES We examined the hypothesis that these augmented responses to O(3) are the result of greater signaling through tumor necrosis factor receptor 2 (TNFR2) and/or interleukin (IL)-13. METHODS We exposed lean wild-type (WT) and TNFR2-deficient (TNFR2(-/...

Journal: :Optics express 2011
Yuliang Gao Alan Pak Tao Lau Shuangyi Yan Chao Lu

A low-complexity feed-forward carrier phase estimation (CPE) technique is presented for dual-polarization (DP)-16-QAM transmission systems. By combining QPSK partitioning, maximum likelihood (ML) detection and phase offset estimation between signals in different polarizations, simulation and experimental results for a 200 Gb/s DP-16-QAM system demonstrate similar linewidth tolerance to the best...

Journal: :Journal of clinical microbiology 1986
M Q Arens E M Swierkosz R R Schmidt T Armstrong K A Rivetna

During two winter seasons, we found that the combination of WI-38 or MRC-5 human lung fibroblasts plus primary rhesus monkey kidney (RhMK) and HEp-2 cell cultures yielded maximal isolation of respiratory syncytial virus. Cytopathic effects (CPE) developed earliest in RhMK cells and slowest in the human fibroblast lines. In RhMK cells, 50% of ultimately positive cultures showed CPE in 5 days, an...

Journal: :Gut 1979
R J Phillpotts J Hermon-Taylor B N Brooke

Homogenates of gut and mesenteric lymph node tissue from patients with Crohn's disease, ulcerative colitis, and control patients were tested for cytopathic effect (CPE) production in a series of cell lines including rabbit ileal and W138 cells. A CPE was produced in W138 cells by tissue homogenates from patients with Crohn's disease, ulcerative colitis, and control patients. Evidence was obtain...

Journal: :Infection and immunity 1992
T A Mietzner J F Kokai-Kun P C Hanna B A McClane

A synthetic peptide homolog corresponding to the C-terminal 30 amino acids of Clostridium perfringens type A enterotoxin (CPE) was conjugated to a thyroglobulin carrier and used to immunize mice. Conjugate-immunized mice produced antibodies which neutralized native CPE cytotoxicity, at least in part, by blocking enterotoxin binding. This peptide may be useful for the development of a vaccine to...

Journal: :Journal of virology 2015
Nicholas L Baird Jacqueline L Bowlin Taylor J Hotz Randall J Cohrs Don Gilden

Infection of human neurons in vitro with varicella-zoster virus (VZV) at a low multiplicity of infection does not result in a cytopathic effect (CPE) within 14 days postinfection (dpi), despite production of infectious virus. We showed that by 28 dpi a CPE ultimately developed in infected neurons and that interferon gamma inhibited not only the CPE but also VZV DNA accumulation, transcription, ...

2012
P. Parameshwar D. Aruna Devi B. Mahipal Reddy K. Sathyanarayana Reddy E. Ramesh G. Narender Naik

The hypoglycemic and anti-lipidemic effect of hydro-ethanolic extract of Ceiba pentandra Linn (FamilySterculiaceae) root extracts (CPE) were investigated in normal and alloxan-induced diabetic rats. In the present study, the animals were divided into normal control, diabetic control, diabetic treated and control treated group (n = 6). Effect of oral administration of CPE (300 mg/kg) for 30 days...

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