Volunteers immunized under chloroquine chemoprophylaxis with Plasmodium falciparum sporozoites (CPS) develop complete, long-lasting protection against homologous sporozoite challenge. Chloroquine affects neither sporozoites nor liver-stages, but kills only asexual forms in erythrocytes once released from the liver into the circulation. Consequently, CPS immunization exposes the host to antigens...

In the past decade, we have witnessed an unparalleled success of information and communication technologies (ICT), which is expected to be even more proliferating and ubiquitous in the future. Among many ICT applications, ICT components embedded into various devices and systems have become a critical one. In fact, embedded systems with communication capability span virtually every aspect of our...

Action mechanisms underlying various biological activities of collagen peptides (CPs) remained to be elucidated. Cytokines may play an important role in mediating these health benefits of CPs. This study aimed to systemically examine the cytokines in skin and blood regulated by CPs intake. Thirteen-month-old female Kunming mice were administered with CPs for 2 months (0 or 400 mg/kg bodyweight/...

AIM Accumulating evidence suggests that predictability of traditional cardiovascular risk factors declines with advancing age. We investigated whether carotid plaque scores (CPSs) were associated with cardiovascular disease (CVD) death in the oldest old, and whether asymmetrical dimethylarginine (ADMA), a marker of endothelial dysfunction, moderated the association between the CPS and CVD death...

Vibrio vulnificus produces a severe septic shock syndrome in susceptible individuals. Virulence of the bacterium has been closely linked to the presence of a surface-exposed acidic capsular polysaccharide (CPS). To investigate whether CPS plays an additional role in pathogenesis by modulating inflammatory-associated cytokine production, studies were initiated in a mouse model and followed by in...

Continuation Passing Style (CPS) is widely used in the semantics of functional programming languages. We emphasize that CPS translates calculus with control operators into a very basic calculus | CPS calculus. In the past literature, CPS calculus appears in various style in di erent situation. We show how they can be considered as the "same" calculus. More precisely, all of them are Curry-Howar...

In this paper, we study the formalization of one-pass call-by-value CPS compilation using higher-order abstract syntax. In particular, we verify mechanically that the source program and the CPS-transformed program have the same observable behavior. A key advantage of this approach is that it avoids any administrative redexes thereby simplifying the proofs about CPS-translations. The CPS transla...

Techniques for depositing silicon into nanosized spaces are vital for the further scaling down of next-generation devices in the semiconductor industry. In this study, we filled silicon into 3.5-nm-diameter nanopores with an aspect ratio of 70 by exploiting thermodynamic behaviour based on the van der Waals energy of vaporized cyclopentasilane (CPS). We originally synthesized CPS as a liquid pr...

CyberPhysical Systems (CPS) consist of a combination of different embedded subsystems, which work independently of each other and also interact with the external environment. Such embedded systems operate in the presence of inherent uncertainty, context dependencies and adversarial certainty arising from both the cyber and physical worlds. Security is one of the key concepts to shield the CPS e...

Reversing tumor-associated immunosuppression seems necessary to stimulate effective therapeutic immunity against lethal epithelial tumors. Here, we show this goal can be addressed using cps, an avirulent, nonreplicating uracil auxotroph strain of the parasite Toxoplasma gondii (T. gondii), which preferentially invades immunosuppressive CD11c(+) antigen-presenting cells in the ovarian carcinoma ...