The clinical and MR findings in an unusual case of gummatous neurosyphilis are reported. A 44-year-old woman suffering from diplopia and right-sided headaches was admitted. Physical examination and routine laboratory parameters were normal except for a third-nerve palsy. MR images revealed a contrast-enhancing lesion of the upper brain stem and third cranial nerve. Differential diagnosis includ...

We report the successful use of bortezomib to treat a patient with multiple myeloma (MM) who had extramedullary relapse (paraspinal and thoracic masses and multiple cranial nerve palsy) after autologous and non-myeloablative allogeneic hematopoietic stem cell transplantation (HSCT).

A 7 day delay occurred in the diagnosis of cephalic tetanus in a 69 year old woman who developed an ipsilateral facial palsy 5 days after a facial laceration. Cranial nerve palsies often precede trismus in this form of tetanus.

Pituitary apoplexy is a serious condition, which if left untreated, might lead to irreversible life-long complications. Hence, pituitary should always be included in the differential diagnoses of patient with an isolated sixth cranial nerve (CN) palsy. This report highlights case presenting CN palsy associated apoplexy. Although adenomas are common, they seldom present abducent without any othe...

Ophthalmoplegic migraine is a rare disorder characterized by childhood onset recurrent attacks of migraineous headaches with paresis of ocular cranial nerves. The third cranial nerve is commonly involved. Involvement of fourth and sixth cranial nerve is uncommon. We present a child with opthalmoplegic migraine with recurrent sixth cranial nerve palsy on two occasions. Neurology Asia 2013; 18(1)...

A 7-year-old boy underwent resection of a posterior fossa medulloblastoma. Two days later, he developed facial diplegia, left abducens nerve palsy, and mild hypalgesia below the neck. MRI documented 2 dot-like ischemic foci in the pons (figure). We diagnosed the unusual bilateral occurrence of Gasperini syndrome, a lesion of the sixth and seventh cranial nerve nuclei and the lateral spinothalam...

Capecitabine is an oral chemotherapeutic agent converted to 5 fluorouracil (5-FU). Neurotoxicity associated with the medication encompasses both central and peripheral nervous systems. We describe a 60 year old man with colonic carcinoma who developed diplopia due to a sixth nerve palsy following the use of capecitabine which is an orally administered prodrug of 5-FU. An MRI of brain did not re...

this is a report of a case with unilateral cavernous sinus thrombosis due to ipsilateral ethmoid sinusitis. a 10 year old female was admitted in our hospital with severe headache, purulent postnasal discharge, right eye proptosis and third cranial nerve palsy in the same eye. she had history of viral upper respiratory tract infection and then acute otitis media which did not improve with routin...