AIMS To determine if cardiac enzymes measured at necropsy could be used to predict early myocardial infarction. METHODS Cardiac enzyme activities were measured in body fluids at necropsy. Coroners' necropsies were grouped by gross and microscopic findings into cases of definite myocardial infarction, cases with occlusive coronary artery atheroma but no identifiable myocardial infarction, and ...

Knitter, A. E., L. Panton, J. A. Rathmacher, A. Petersen, and R. Sharp. Effects of b-hydroxy-b-methylbutyrate on muscle damage after a prolonged run. J Appl Physiol 89: 1340–1344, 2000.—This study examined the effects of supplemental b-hydroxy-b-methylbutyrate (HMB) on muscle damage as a result of intense endurance exercise. Subjects (n 5 13) were paired according to their 2-mile run times and ...

OBJECTIVE To determine whether serum myoglobin, creatine kinase, and creatine kinase-MB measured at admission by rapid, compact, and easy to use automated quantitative analysers (results within 10 min) helped the early identification of acute myocardial infarction. The results were compared with the data obtained from the electrocardiograms recorded at admission. DESIGN A prospective study. ...

A total of 979 cardiac profiles were reviewed. Seventeen cases were found to have elevated CK-BB by electrophoresis and were misidentified by the immunoinhibition/immunoprecipitation technique as elevated creatine phosphokinase (CK-MB). Eleven of the 17 cases also had elevated lactate dehydrogenase (LD) LD-5/LD-1 ratio; five cases were motor vehicle accident (MVA), four cases were prostatic car...

background: the cardiac effects simultaneously occurring during experimental hypertension and diabetes have rarely been investigated. this study aimed at examining the effects of short-term renovascular hypertension and type 2 diabetes on cardiac functions. methods: five groups (7 each) of male sprague-dawley rats, including a control group, a diabetes (induced by streptozocin and nicotinamide)...

Fractional extractions of heart muscle have revealed that about 30% of cellular creatine phosphokinase activity are located in mitochondria and about 20% are bound to myofibrils [ 1,2] . The presence of significant creatine phosphokinase activity in heart and skeletal muscle myofibrils has been demonstrated also in studies of isolated myofibrillar preparations [ 1,3,4] . This particulate enzyme...

Commiphora mukul commonly known as Guggul is one of the oldest and commonly consumed herb for promoting heart and vascular health. Present study was undertaken to evaluate cardioprotective potential of Commiphora mukul against isoprenaline-induced myocardial necrosis in rats. Wistar albino rats were divided into three main groups: sham (saline only), isoprenaline control (saline and isoprenalin...

BACKGROUND Vaginal sonograghy and serial -hCG are the most common diagnostic methods for ectopic pregnancy but about 50% of cases are initially misdiagnosed. In tubal pregnancy the zygote lies next to the muscular layer, and this invasion causes an increase in creatine phosphokinase (CPK) in blood. OBJECTIVE assessment of CPK and its isoenzyme CPK-MB as a diagnostic marker for tubal pregnancy...

BACKGROUND The cardioprotective effect of ischemic preconditioning has been known for many years. Since the temporary ischemia in the heart may cause lethal cardiac effects, the idea of creating ischemia in organs far from the heart such as limbs was raised as remote ischemic preconditioning (RIPC). We hypothesized that the extension of RIPC has more cardioprotective effect in patients undergoi...

CONTEXT AND OBJECTIVE Neonatal hypoxic-ischemic encephalopathy is associated with high morbidity and mortality. Studies have shown that therapeutic hypothermia decreases neurological sequelae and death. Our aim was therefore to report on a three-year experience of therapeutic hypothermia among asphyxiated newborns. DESIGN AND SETTING Retrospective study, conducted in a university hospital. ...