نتایج جستجو برای: cross protection

تعداد نتایج: 662621  

Journal: :Microbiological research 2010
Angela A Parry-Hanson Piet J Jooste Elna M Buys

Cross-protection of acid-adapted Escherichia coli O157:H7 against inimical stresses is mediated by the glucose-repressed sigma factor RpoS. However, many food systems in which E. coli O157:H7 occurs are complex and contain glucose. This study was aimed at investigating the contribution of acid and lactoperoxidase (LP)-inducible genes to cross-protection of E. coli O157:H7 against LP system and ...

Journal: :The Journal of infectious diseases 2011
Amporn Srikram Kunkun Zhang Thanatchaporn Bartpho Miranda Lo David E Hoke Rasana W Sermswan Ben Adler Gerald L Murray

BACKGROUND Leptospira species cause leptospirosis, a zoonotic disease found worldwide. Current vaccines against leptospirosis provide protection only against closely related serovars. METHODS We evaluated an attenuated transposon mutant of Leptospira interrogans serovar Manilae (M1352, defective in lipopolysaccharide biosynthesis) as a live vaccine against leptospirosis. Hamsters received a s...

Journal: :Journal of virology 2014
Eun Hye Kim Hae-Jung Park Gye-Yeong Han Man-Ki Song Alexander Pereboev Jeong S Hong Jun Chang Young-Ho Byun Baik Lin Seong Huan H Nguyen

UNLABELLED Influenza vaccines aimed at inducing antibody (Ab) responses against viral surface hemagglutinin (HA) and neuraminidase (NA) provide sterile immunity to infection with the same subtypes. Vaccines targeting viral conserved determinants shared by the influenza A viruses (IAV) offer heterosubtypic immunity (HSI), a broad protection against different subtypes. We proposed that vaccines t...

2000
Takahiro Shinagawa Kenji Kono Takashi Masuda

This paper describes a mechanism for protecting against malicious mobile code. As mobile code is linked with a hosting application and executed in the same process, a fine-grained protection domain providing an intra-process protection is required to prevent a malicious mobile code from unauthorized access. This paper introduces a multi-protection page table: a mechanism of virtual memory that ...

ژورنال: پیاورد سلامت 2017
امیری, فاطمه, توحیدنیا, محمد رسول, خوش گرد, کریم, هرمزی مقدم, زینب,

Background and Aim: More than 80% of patients need to take x-rays during their diagnosis and treatment stages. Due to the biological effects of ionizing radiation, observance of radiation protection principles are necessary. The observance of radiation protection principles in intensive care units at Imam Reza hospital of Kermanshah in 2014 was evaluated in this study. Materials and Methods: I...

2015
Mark Jit Marc Brisson Jean-François Laprise Yoon Hong Choi

OBJECTIVE To investigate the incremental cost effectiveness of two dose human papillomavirus vaccination and of additionally giving a third dose. DESIGN Cost effectiveness study based on a transmission dynamic model of human papillomavirus vaccination. Two dose schedules for bivalent or quadrivalent human papillomavirus vaccines were assumed to provide 10, 20, or 30 years' vaccine type protec...

2009
Karen J Fairlie-Clarke David M Shuker Andrea L Graham

Antigen specificity of adaptive immune responses is often in the host's best interests, but with important and as yet unpredictable exceptions. For example, antibodies that bind to multiple flaviviral or malarial species can provide hosts with simultaneous protection against many parasite genotypes. Vaccinology often aims to harness such imprecision, because cross-reactive antibodies might prov...

Journal: :Cell reports 2016
Katie A Howell Xiangguo Qiu Jennifer M Brannan Christopher Bryan Edgar Davidson Frederick W Holtsberg Anna Z Wec Sergey Shulenin Julia E Biggins Robin Douglas Sven G Enterlein Hannah L Turner Jesper Pallesen Charles D Murin Shihua He Andrea Kroeker Hong Vu Andrew S Herbert Marnie L Fusco Elisabeth K Nyakatura Jonathan R Lai Zhen-Yong Keck Steven K H Foung Erica Ollmann Saphire Larry Zeitlin Andrew B Ward Kartik Chandran Benjamin J Doranz Gary P Kobinger John M Dye M Javad Aman

Previous efforts to identify cross-neutralizing antibodies to the receptor-binding site (RBS) of ebolavirus glycoproteins have been unsuccessful, largely because the RBS is occluded on the viral surface. We report a monoclonal antibody (FVM04) that targets a uniquely exposed epitope within the RBS; cross-neutralizes Ebola (EBOV), Sudan (SUDV), and, to a lesser extent, Bundibugyo viruses; and sh...

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