objectives thus, the present study aimed to determine if fas and fasl promoter polymorphisms are associated with the clinical outcome of hbv infection. patients and methods dna samples were obtained from the infected individuals including chronic carrier (n = 50), chronic hepatitis (n = 50), cirrhosis (n = 25), naturally recovered (n = 26) and compared with those of their matched healthy contro...

in this study at first , an azo dye, 2,7- naphthalenediol, 2-[(4-bromophenyl)azo (bpand) as a ligand has been synthesized by addition of p-bromoaniline to the modified montomorillonite k10 clay. this ligand was characterized using 1h-nmr, uv-vis and ir spectroscopies. subsequently, its interaction with calf thymus deoxyribonucleicacid ,ct-dna was investigated in 5 mm phosphate buffer solution, ...

Background: Male infertility has many causes, including genetic infertility. The NOP2/Sun domain family, member7 (Nsun7) gene, which encodes putative methyltransferase Nsun7, has a role in sperm motility. The aim of the present study was to investigate the effect of the T26248G polymorphism on Nsun7 protein function and its role in male infertility. Materials and Methods: Semen samples were col...

Background: Natural killer (NK) cells are the effector cells of innate immunity that respond to infection and tumor. Interactions between killer cell immunoglobulin like receptors (KIR) and human leukocyte antigen (HLA) class I molecules regulate NK cells responses to eliminate infected and transformed cells. Objective: To investigate the impact of KIR genes, HLA ligand genes, and KIR-HLA combi...

In this study at first , an azo dye, 2,7- naphthalenediol, 2-[(4-Bromophenyl)azo (BPAND) as a ligand has been synthesized by addition of p-Bromoaniline to the modified montomorillonite K10 clay. This ligand was characterized using 1H-NMR, UV-Vis and IR spectroscopies. Subsequently, its interaction with calf thymus deoxyribonucleicacid ,ct-DNA was investigated in 5 mM phosphate buffer solution, ...

The zinc(II) complex [Zn2(dmdtc)2(μ-dmdtc)2] has been synthesized directly from thiram ligand, containing a disulfide bond {dmdtc = N,N-dimethyldithiocarbamate; thiram = N,N-tetramethylthiuram disulfide}, and characterized by elemental analysis and spectroscopic methods. Surprisingly thiram, undergoes a reductive disulfide bond scission upon reaction with Zn2+ in methanolic media to give the [Z...

The solvent extraction of rare earth metal ions from nitrate solutions by 5.11.17.23-tetra-tert-butyl-25,27-bis(diethylcarbamoylmethoxy)-26,28-dihydroxycalix[4]arene (L) in 1,2-dichloroethane has been investigated. The alalysis of the extraction equilibrium obtained from a mixture of La3+, Eu3+, Er3+ and Y3+ revealed that the extracted species hav...

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), a member of TNF family, is an interesting ligand which selectively induces apoptosis in tumor cells and, therefore, it has been developed for cancer therapy. This ligand has been produced by various hosts such as E.coli. However, protein expression in E.coli cytoplasm leads to problems such as incorrect folding, reduction in biolo...