نتایج جستجو برای: cystic endometrial hyperplasia
تعداد نتایج: 104225 فیلتر نتایج به سال:
AIMS To determine the type of endometrial abnormalities associated with prolonged tamoxifen treatment and to investigate the correlation between tamoxifen dose and any abnormalities detected. METHODS Endometria from 19 prospectively collected breast cancer patients treated with tamoxifen were ascribed a pathological diagnosis and the findings compared with those in a control group matched for...
OBJECTIVES Endometrial cancer is one of the most common malignancies in women. The prevention has failed so far to develop an effective screening program and its incidence is rising in proportion to the incidence of cervical cancer. In recent years the investigation of malignancy genomics (genetic and epigenetic changes) has become the main focus of scientists because of its high sensitivity an...
cality and glandular complexity in endometrial hyperplasia are associated with an increased risk of endometrial cancer [1,2]. Moreover, the possible existence of occult endometrial carcinoma or the risk of progression to carcinoma in complex or atypical endometrial hyperplasia has been a rationale to offer invasive surgery when a patient was found to have these histologic features [1]. Interest...
Dysfunctional uterine bleeding (DUB) is defined as heavy and or irregular menstruation in the absence of recognizable pelvic pathology, pregnancy or general bleeding disorder. Hyperplastic endometrium is abnormal histology finding found in DUB. Out of three type of hyperplasia, atypical type is associated with co-existent ca endometrium and the chance of progression to ca endometrium is very hi...
Objective. To evaluate accuracy of transvaginal sonography (TVS) and hysteroscopy in detection of intrauterine pathology in infertile women. Subjects and methods. This retrospective study was conducted in 56 infertile women with abnormal transvaginal ultrasound findings of the uterine cavity which was performed during the midfollicular phase as a part of routine infertility workup. Hysteroscopy...
Nucleolar organizer regions (NORs) are loops of DNA that transcribe to ribosomal RNA. They are associated with nonhistone nucleoproteins which can be stained with silver (AgNORs). The present retrospective study was done to study the efficacy of AgNOR technique in differentiating between non neoplastic and neoplastic lesions of endometrium and to assess the relationship between AgNOR counts and...
Tamoxifen (TAM) is widely used as adjuvant breast cancer therapy after surgery and as a chemopreventive agent in women of child-bearing age. However, TAM therapy has been shown to result in an increased incidence of endometrial carcinoma in women. The present study was designed to investigate the effects of TAM (5 mg/kg and 7.5 mg/kg body wt) given i.g. to pregnant CD-1 mice (1x/day, days 12 th...
Introduction: The process of discriminating among benign and malignant hyperplasia begun with subjective methods using light microscopy and is now being continued with computerized morphometrical analysis requiring some features. One of the main features called Volume Percentage of Stroma (VPS) is obtained by calculating the percentage of stroma texture. Currently, this feature is calculated ...
Endometrial hyperplasia is of clinical significance because it is often a precursor lesion to adenocarcinoma of the endometrium. Making the distinction between hyperplasia and true precancerous lesions or true neoplasia has significant clinical effect because their differing cancer risks must be matched with an appropriate intervention to avoid undertreatment or overtreatment. Pathologic diagno...
Background: The aim of the conservative treatment is the regression of the hyperplastic to normal endometrium. Conservative treatment of endometrial hyperplasia is based on the administration of agents with either antioestrogenic action or direct anti-proliferative effect on the endometrium. Progestagens have been used widely in the treatment of endometrial hyperplasias. Materials and Methods: ...
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