نتایج جستجو برای: cytogenetic
تعداد نتایج: 12450 فیلتر نتایج به سال:
Specific cytogenetic clones might distinguish patients with unrecognized Fanconi anemia (FA) who present with acute myeloid leukemia (AML) from those with sporadic AML. Cytogenetic reports in literature cases of FA and AML were compared with de novo cases enrolled on CCG-2961. Gain of 1q, gain of 3q, monosomy 7, deleted 7q, gain of 13q, and deleted 20q were more frequent in FA AML; t(8;21), tri...
The Committee for the International System for Human Cytogenetic Nomenclature (ISCN) has recently met and published a revised version, ISCN 2009. Multiple changes in nomenclature guidelines are presented in that updated version. This review will highlight changes to the idiograms and specific changes in respective chapters of the 2009 version compared with the previous version of the ISCN publi...
A brief description of chromosome aberrations and sister chromatid exchange (SCE) as cytogenetic endpoints for evaluation of DNA damaging agents is presented. Problems associated with the use of cytogenetic assays as population monitors of radiation and chemical exposures are discussed. Adequate cell sample size requirements and accurate assessment of cummulative exposure effects with increasin...
Bugs (Insecta: Heteroptera) are frequently used as examples of unusual cytogenetic characters, and the family Cimicidae is one of most interest in this respect. We have performed a cytogenetic study of the common bed bug Cimex lectularius Linnaeus, 1758 using both classical (Schiff-Giemsa and AgNO3-staining) and molecular cytogenetic techniques (base-specifi c DAPI/CMA3 fl uorochromes and FISH ...
introduction: about half of acute myeloid leukemia (aml) adult patients have no cytogenetic abnormalities as a main determinant of complete remission after treatment, so other markers are needed such as flt3-itd (fms-like tyrosine kinase3-internal tandem duplication) mutations in patients with normal karyotype. the objective of this study was assessing the frequency of flt3-itd mutations and it...
The latest edition of the International System for Human Cytogenetic Nomenclature, ISCN 2013, has recently been published following a thorough revision of the 2009 issue and the incorporation of suggestions from the community by the current standing committee. This review will highlight the multiple nomenclature changes in the respective chapters of the 2013 version compared to the previous ver...
A classification of chronic (mature) B-cell lymphoproliferative disorders based on reproducible morphologic and immunologic criteria was proposed by the FAB group in 1989. Ever since a number of cytogenetic studies disclosed a remarkable degree of heterogeneity within each disease category. In this table the main cytogenetic entities of chronic lymphocytic leukemia and related disorders, B-cell...
Cytogenetic evaluation is an important step in the diagnosis of infertile or sterile animals. Moreover, the analysis of sex chromosomes is crucial for a proper classification of disor‐ ders of sex development (DSD). For many years, chromosome studies mainly addressed the livestock species, while recently, increasing interest in such analysis in companion an‐ imals is observed. New molecular and...
Abstract It is not known when the polyploid coast redwood ( Sequoia sempervirens ) evolved from its diploid ancestors, and what type of polyploidy. Whether close relatives , giant sequoia Sequoiadendron giganteum dawn Metasequoia glyptostroboides ), have possibly contributed to ancestry hexaploid remains an open question. The nature hexaploidy in has baffled biologists for more than a century. ...
Aim. The main goal of this study was to the anti-radiation effect guaninium-zinc chloride complex on cytogenetic changes in irradiated rats. Methods. White rats Wistar line with an average weight 110-125 grams served as material for detection complex. Animals were injected intraperitoneally solutions at a concentration 40 mg/kg 2 hours before irradiation and subjected general uniform gamma from...
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