quaternary ammonium compounds (qacs) are employed both as disinfectants for manual processing lines and surfaces in the food industry, and in human medicine area. qacs also cause cell death by protein denaturation . one of the qac is cetyl trimethyl ammonium bromide (ctab) that appears to rapture the cell membrane. the primary site of action of ctab has been suggested to be the lipid components...

Dengue virus produces a mild acute febrile illness, dengue fever (DF) and a severe illness, dengue hemorrhagic fever (DHF). The characteristic feature of DHF is increased capillary permeability leading to extensive plasma leakage in serous cavities resulting in shock. The pathogenesis of DHF is not fully understood. This paper presents a cascade of cytokines, that in our view, may lead to DHF. ...

Background Nurses and other first responders are at high risk of exposure to the SARS-CoV2 virus, many have developed severe COVID-19 infection. A better understanding factors that increase infection after virus could help address this. Although several such as obesity, diabetes, hypertension been associated with an increased infection, develop without established factors. As inflammation cytok...

Pemphigus vulgaris (PV) is a chronic autoimmune blistering disease of the skin, in whichloss of adhesion between keratinocytes is caused by autoantibodies. It has been hypothesizedthat cytokines play an essential role in the pathogenesis of PV. This study aimed to investigatethe other immunopathological aspects of PV by determining the serum levels of cytokines inPV patients to find another tre...

Cytokines are locally produced in the anterior pituitary and act through para-/autocrine mechanisms to modulate cell growth and hormone production. 5'-Deiodinases type I (D1) and type II (D2) are also expressed in the anterior pituitary and play an integrative role in the regulation of hormone production and pituitary feedback. D1 activity is known to be regulated by proinflammatory cytokines i...

The Mössbauer spectra of nanoferrite materials such as Ni0.25Mn0.75Fe2O4, Co0.5Mn0.5Fe2O4 and Ni0.4Co0.6Fe2O4 have been reported and the above materials were prepared by sol-gel combustion method using metal nitrates as source material and Polyvinyl alcohol(PVA) as...

Pemphigus vulgaris (PV) is a chronic autoimmune blistering disease of the skin, in whichloss of adhesion between keratinocytes is caused by autoantibodies. It has been hypothesizedthat cytokines play an essential role in the pathogenesis of PV. This study aimed to investigatethe other immunopathological aspects of PV by determining the serum levels of cytokines inPV patients to find another tre...

in this study, we aimed at studying the benefit of urtica dioica root extract in the management of allergic rhinitis. in a randomized double blind clinical trial, 74 patients with the signs and symptoms of allergic rhinitis and a positive skin prick test were randomly divided into 2 groups. the study group was treated with routine allergic rhinitis treatment and nettle root extract (urtidin®, b...

objective(s):intermittent hypoxia (ih), caused by obstructive sleep apnea (osa), could cause hippocampus or neuron damage through multiple signaling pathways, while the underlying mechanisms are still unclear. thus, the present study aimed to explore the effect of ih on the biological functions of microglia cells. materials and methods:cell proliferation of bv2 cells after exposure to ih were o...