نتایج جستجو برای: cytotoxic activity

تعداد نتایج: 1172874  

Journal: :Journal of Clinical Laboratory Analysis 2004

توپاکتاس, مهمت, نوری زاده تازه کند, مصطفی,

Introduction: Tetracyclic antidepressants-mirtazapin is one of antidepressants drug that exhibits both noradrenergic and serotonergic activity. It is commonly used to treat major depressive disorder. The genotoxic effect of mirtazapine has not been examined previously. The purpose of this study was to investigate the genotoxic and cytotoxic effects of mirtazapine on human peripheral blood lymph...

The current study evaluated the general toxicity, antioxidant, antimicrobial, and cytotoxic activity of extracts obtained from the rhizomes of Eremostachys azerbaijanica (Labiatae) as well as analyzed the potent extracts using GC-MS. Extracts of E. azerbaijanica in n-hexane, dichloromethane (DCM) and methanol (MeOH) were prepared using a Soxhlet apparatus. The antioxidant activity of the extrac...

 Caffeic acid phenethyl ester(CAPE) suppresses the growth of transformed cells such as human breast cancer cells, hepatocarcinoma , myeloid leukemia, colorectal cancer cells, fibrosarcoma, glioma and melanoma. A group of heterocyclic esters of caffeic acid was synthesized using Mitsunobu reaction and the esters were subjected to further structural modification by electrooxidation of the catecho...

Journal: :research in pharmaceutical sciences 0

previous studies have indicated that some species of cuscuta possess anticancer activity on various cell lines. due to the lack of detailed researches on the cytotoxic effects of cuscuta chinensis and cuscuta epithymum , the aim of the present study was to evaluate cytotoxic effects of chloroform and hydroalcoholic extracts of these plants on the human breast carcinoma cell line (mda-mb-468), h...

Journal: :the iranian journal of pharmaceutical research 0
ines skandrani faculty of dental medecine monastir ludovik leloup inserm umr 911 – cro2 (centre de recherche en oncologie biologique et oncopharmacologie) faculté de pharmacie – 27 bd jean moulin – cs 30064 - 13385 marseille cedex 05 – france herve kovacic inserm umr 911 – cro2 (centre de recherche en oncologie biologique et oncopharmacologie) faculté de pharmacie – 27 bd jean moulin – cs 30064 - 13385 marseille cedex 05 – france marie-geneviève dijoux-franca laboratory of pharmacognosy lyon, france kamel ghedira faculty of pharmacy tunisia leila chekira faculty of pharmacy tunisia

in this study, we investigate the potential of moricandia arvensis methanol leaf extract (meohl) on calpain activity, melanin biosynthesis and dna mutagenicity. cytotoxic effect and measurement of reactive oxygen species (ros) induced by lucigenin in colorectal cells (be) were also determined. in addition the chemical analysis of the extract was also studied and the chemical profile illustrates...

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