The first line treatment of obstructive sleep apnea (OSA) is continuous positive airway pressure (CPAP), which has been shown to reduce daytime sleepiness and improve quality of life. However, the majority of patients with CVD and concomitant OSA do not experience daytime sleepiness, i.e. they are asymptomatic, and it has still been hardly debated whether or not all CVD patients with OSA should...

OBJECTIVES To assess the therapeutic efficacy of modafinil in the treatment of increased daytime sleepiness in patients with Parkinson's disease (PD). DESIGN Double-blind, randomized, placebo-controlled crossover study with two 2-week treatment blocks, separated by a 2-week washout phase. SETTING Tertiary Parkinson's disease care center and sleep laboratory at university hospital neurology ...

Excessive daytime sleepiness (EDS) has not been investigated using objective tests in myasthenia gravis (MG). We investigated whether objective measurements of somnolence better detected abnormalities compared with sleepiness questionnaires in MG, and determine if MG patients have EDS. Eight patients with mild-to-moderate MG were recruited. Patients completed maintenance of wakefulness, overnig...

Measures of excessive daytime sleepiness, neuropsychologic function, and mood were assessed in twenty-two persons with mid-stage Parkinson's disease (PD) and sixteen age-matched healthy controls. Levodopa dose equivalents (LDE) were computed for the patients. While Epworth sleepiness score (ESS), Mini Mental State Exam, logical memory, Stroop, and the mood scales, reliably distinguished patient...

There is considerable interest in the association of snoring and health consequences that have been linked to more severe sleep-disordered breathing, including obstructive sleep apnoea syndrome. The goal of this investigation was to assess the independent association of heavy, habitual snoring and daytime sleepiness. For this, a cross-sectional, population based study of snoring, sleepiness and...

Experimental fasting has been shown to alter the sleep-wakefulness pattern in various species. As fasting during Ramadan is distinct from experimental fasting, the physiological and behavioural changes occurring during Ramadan fasting may differ from those occurring during experimental fasting. There has been increased interest in recent years in sleep changes and daytime sleepiness during Rama...

BACKGROUND Cardiovascular disease (CVD) is the leading cause of death among American Indians. It is not known if symptoms of insomnia are associated with CVD in this population. METHODS We examined 449 American Indians aged ≥ 55 years from the Native Elder Care Study. The main outcome-of-interest was self-reported CVD. RESULTS Short sleep duration, daytime sleepiness, and difficulty falling...

background : there are a few studies to assess nurses’ sleep quality and sleepiness in the iranian context. this study thus was carried out to examine the prevalence of sleepiness and sleep quality among nurses in south east of iran.   subjects and methods : the study applied a descriptive, explorative design.252 nurses randomly selected from kerman university hospitals during winter 2009. usin...