A dense network of macrophages and dendritic cells (DC) expressing the chemokine receptor CX3CR1 populates most tissues. We recently reported that CX3CR1 regulates the abundance of CD11c(+) DC in the kidney and thereby promotes renal inflammation in glomerulonephritis. Given that chronic inflammation usually causes fibrosis, we hypothesized that CX3CR1 deficiency should attenuate renal fibrosis...

Amyotrophic lateral sclerosis (ALS) is a rare degenerative disorder characterized by loss of upper and lower motor neurons. Neuroimaging has provided noticeable evidence that ALS is a complex disease, and shown that anatomical and functional lesions extend beyond precentral cortices and corticospinal tracts, to include the corpus callosum; frontal, sensory, and premotor cortices; thalamus; and ...

the aim of this paper is to design a fractional order sliding mode controllers (fosmc)for a class of dc-dc converters such as boost and buck converters. firstly, the control lawis designed with respect to the properties of fractional calculus, the design yields an equiv-alent control term with an addition of discontinuous (attractive) control law. secondly, themathematical proof of the stabilit...

This paper introduces an implementation of a closed group distributed anonymous wiki based on a Dining Cryptographer (DC) network. We argue that such a wiki application particularly suits the properties of a DC network, e.g., performance is less important, and broadcast communication is needed by default.

The transition from traditional AC distribution system to future mature AC/DC hybrid mode is an effective means solve the challenges of high penetration distributed energy, diversification energy types, requirements power quality and supply reliability.AC / DC can be used in many scenarios by virtue its technical advantages. This paper analyzes typical application network perspective "source lo...

A low-voltage low-power analogue-baseband chain designed for IEEE 802.11a/b/g wireless local-area network (WLAN) receivers is described. It features architecturally a ‘two-step channel selection’ to complement the radio front-end, and a flexible intermediate frequency (IF) reception capability to alleviate the cancellation of frequency and DC-offset. In circuit implementation, a double-quadratu...

This research focuses on developing a proportional integral derivative controller based single artificial neural network (PID-SANN). The proposed control strategy drives the direct current (DC-DC) boost converter output voltage to follow desired reference value. calculates PID gains via learning algorithm an single-neuron network, which overcomes computational complexity of using analytical met...