PURPOSE To investigate macular ganglion cell-inner plexiform layer (mGCIPL) thickness in glaucomatous eyes with visible localized retinal nerve fiber layer (RNFL) defects on stereophotographs. METHODS 112 healthy and 149 glaucomatous eyes from the Diagnostic Innovations in Glaucoma Study (DIGS) and the African Descent and Glaucoma Evaluation Study (ADAGES) subjects had standard automated peri...

In this paper, an atomistic based finite element model is developed to investigate the influence of topological defects on mechanical properties of graphene. The general in-plane stiffness matrix of the hexagonal network structure of graphene is found. Effective elastic modulus of a carbon ring is determined from the equivalence of molecular potential energy related to stretch and angular defor...

Ophthalmoscopic scrutiny of the nerve fiber layer was first advocated by Hoyt, over 30 years ago. In the following years, the importance of localized defects of the retinal nerve fiber layer (NFL) for the diagnosis of glaucoma has been demonstrated in many studies. The evaluation of the NFL, though relatively difficult and subjective, has become routine in the common ophthalmic examination. We ...

The cause for wide variations in the zig-zag defect density in SSFLC devices using the same alignment layer material is investigated. In this paper, we show how the topography of the surface layer due to imperfect coating techniques and materials promotes the formation of zig-zag defects. We show that if the alignment surface slope is greater than the pretilt, high densities of zig-zag defects ...

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In this study we show that postnatal development of cerebellar granule neurons (GNs) is defective in Npc1(-/-) mice. Compared to age-matched wild-type littermates, there is an accelerated disappearance of the external granule layer (EGL) in these mice. This is due to a premature exit from the cell cycle of GN precursors residing at the level of the EGL. As a consequence, the size of cerebellar ...

Bearing manufacturing requires strict adherence to the technological standards and quality control of products at all stages processing. One most accurate environmentally friendly monitoring methods in bearing production is eddy current method. When using this method, a large array numerical data generated that reflects information on physical mechanical conditions surface. Thus, defect detecti...

OBJECTIVES This study was conducted to evaluate the effect of barrier membranes on sandwich bone augmentation (SBA) for the treatment of implant dehiscence defects. MATERIAL AND METHODS Twenty-six implant-associated buccal dehiscence defects in 22 patients were treated according to the SBA concept - mineralized human cancellous allograft (inner layer), mineralized human cortical allograft (ou...

BACKGROUND The aim of this study was to demonstrate the relationship between topographic reduction in macular ganglion cell complex (GCC) thickness as detected with spectral-domain optical coherence tomography and visual field defects caused by ischemic occipital cortical injury. METHODS This study was a retrospective review of all patients who presented to our eye institution between January...

Objective and sensitive assessment of cartilage repair outcomes lacks suitable methods. This study investigated the feasibility of 3D ultrasound biomicroscopy (UBM) to quantify cartilage repair outcomes volumetrically and their correlation with established classification systems. 32 sheep underwent bilateral treatment of a focal cartilage defect. One or two years post-operatively the repair out...