PURPOSE To investigate the nature and origin of the vitreous membranes in mice with knock-out of the Norrie gene product (ND mice). METHODS Eighty-two eyes of ND mice of different age groups (postnatal day [P]0-13 months) and 95 age-matched wild-type control mice were investigated. In vitreoretinal wholemounts and in sagittal sections, vessels and free cells were visualized by labeling for le...

This 26-wk observational study in children and adolescents with type 1 diabetes (T1D) in Sweden investigated the safety and efficacy of insulin detemir (IDet) in newly diagnosed (ND) patients and those with established diabetes (ED) switching to IDet. A total of 159 patients initiated IDet as part of basal-bolus therapy, 59 in the ND stratum (mean age 9.7 yr) and 97 in the ED stratum (mean age ...

Young growing animals appear to have significantly reduced "nutritional to short periods of unstressed starvation compared with adults, with resultant growth arrest and/or atrophy of diaphragm (Dia) muscle fibers. The aim of this study was to assess in an adolescent rat model of acute nutritional deprivation (ND; 72 h) the impact of insulin-like growth factor I (IGF-I), with or without added gr...

This paper provides an introduction to the ARK Smart Information System (SIS). It describes the business context in whichthe technology was conceived, and how the system addresses those needs. It outlines the important technology principles, and thebenefits of adopting such principles in a business environment. Finally it discusses the relevance of the technology to the thinkingbehi...

Newcastle disease virus (NDV) infects most avian species. The serious consequence is the disease (frequently fatal) that occurs when virulent strains of the virus infect domestic chickens. The epidemiology of Newcastle disease (ND) in commercial chickens is fairly well understood. Infected chickens are the usual source of virus, which can be transported mechanically by fomites or by people. Pre...

introduction: various methods have been used for the treatment of dentine hypersensitivity such as dentifrices, sealants and different types of lasers. the aim of this study was to evaluate the effect of neodimium:yttrium-aluminium-garnet (nd:yag) laser in association with graphite on the dentin morphologic changes. methods: in this experimental in vitro study, 16 freshly extracted third molars...

[(18)F]MPPF PET has previously been used to identify the epileptic lobe in temporal lobe epilepsy (TLE) patients at the group level. This study aims to validate the visual analysis of [(18)F]MPPF PET in the assessment of individual TLE patients for their suitability to undergo temporal lobe resection. Forty-two patients suffering from TLE and 18 control subjects matched for age and gender were ...