Introduction . 13q14 deletion is the most common chromosomal abnormality in chronic lymphocytic leukemia (CLL), and as sole determines favorable prognosis of disease. Using molecular genetic methods two subtypes were identifi ed based on size lost material: small (type I) with involvement D13S319 segment containing MIR15A / MIR16-1 DLEU1 genes large II) centromeric region involving RB1 gene. Da...

the third person singular enclitic verb /-ast/ which is equivalent to english verb “is” undergoes the highest number of  phonological processes among persian enclitic forms of the verb “boudan” (to be); it changes to [as] in one environment, to [s] in another, and to [e] in four environments. deletion of /t/ is common in all six contexts. these different pronunciations are determined by various...

duchene and becker muscular dystrophy (dmd and bmd) are x-linked conditions that result from a defect in the dystrophin gene located on xp21. dmd is the most frequent neuromuscular disease in humans (1/3500 male newborns). in approximately 65% of dmd and bmd patients, deletions in the dystrophin gene have been identified as the molecular determinant. population-based variations in frequency and...

background: haemophilia a (ha) is an x-linked bleeding disorder caused by the absence or reduced activity of coagulation factor viii (fviii). coagulation factors are a group of related proteins that are essential for the formation of blood clots. the aim of this study was to genotype the coagulation factor viii gene mutations using inverse shifting pcr (is-pcr) in an iranian family with severe ...

To study nitrogen contribution to cucumber derived from fixation of Paenibacillus polymyxa WLY78. The nif gene cluster deletion mutant (?nifB-V) WLY78 was constructed by a homologous recombination method. effects plant-growth promotion were investigated greenhouse experiments. estimated 15N isotope dilution method (also being called the natural abundance technique). Deletion P. resulted in comp...

This study is entitled “Deletion and Change of Sounds the Loanwords into Kurdish Language”, which a statistical analytic study. Study instruments have been allocated for words borrowed from English language entered language. The comes within field phonology has worked on according to descriptive manner. intends respond question extend phenomenon deletion changing sounds happen that For this pur...

Levenshtein introduced the problem of constructing k-deletion correcting codes in 1966, proved that optimal redundancy those is O(k log N) for constant k, and proposed an single-deletion code (using so-called VT construction). However, remained open. Our key contribution a major step towards complete solution to this longstanding open k. We present has 8 klog N + o(log when k = o(?{loglog N}) e...

This paper investigates the problem of correcting multiple criss-cross insertions and deletions in arrays. More precisely, we study unique recovery $n \times n$ arrays affected by notation="LaTeX">${t}$ <italic xmlns:xlink="http://www...

in order to simplify the pronunciation ofthe adult&apos;s words,children use phonological processes inthe initial years oftheir speech growth.the present study aims at considering phonological processes ina group oftwo tofour-year old farsi speaking children.the results indicate that itisnot possible to correctly and precisely account forthe occurrences ofsuch processes in children’s pronunciat...

Familial adenomatous polyposis (FAP) is a hereditary syndrome characterized by the presence of multiple polyps in colon. The main cause disease germline mutation APC gene. Here we report 4 unrelated FAP patients with different large deletions gene detected Multiplex Ligation-dependent Probe Amplification (MLPA) method: deletion exons 7-15, promoters B, A, and 5'-UTR region promoter B (in 2 pati...