ABSTRACT We use Gaia photometry and astrometry to estimate the vertical spatial structure of Milky Way at Solar radius, formally accounting for sample incompleteness (the selection function) parallax measurement uncertainty. Our results show impressive precision demonstrating power data. However, systematic errors dominate parameter value uncertainties. thoroughly test quantify impacts all The ...

We overview recent results on intrinsic frictional properties of adsorbed monolayers, composed of mobile hard-core particles undergoing continuous exchanges with a vapor phase. In terms of a dynamical master equation approach we determine the velocity of a biased impure molecule-the tracer particle (TP), constrained to move inside the adsorbed monolayer probing its frictional properties, define...

Intracellular transport along microtubules or actin filaments, powered by molecular motors such as kinesins, dyneins or myosins, has been recently modeled using one-dimensional driven lattice gases. We discuss some generalizations of these models, that include extended particles and defects. We investigate the feasibility of single molecule experiments aiming to measure the average motor densit...

We present the case of a 60-year-old man with metastatic neuroendocrine tumor of the ileum following ileal resection, being evaluated for 177Lu-based peptide receptor radionuclide therapy. 68Ga-DOTANOC PET/CT showed focal increased tracer uptake in the scrotal region without any morphologic changes on the corresponding CT images. Similar increased tracer uptake was seen on...

UNLABELLED The ability to noninvasively measure endogenous pancreatic β-cell mass (BCM) would accelerate research on the pathophysiology of diabetes and revolutionize the preclinical development of new treatments, the clinical assessment of therapeutic efficacy, and the early diagnosis and subsequent monitoring of disease progression. The vesicular monoamine transporter type 2 (VMAT2) is coexpr...

UNLABELLED (S)-(11)C-CGP12388 ((11)C-CGP12388) was recently developed as an in vivo PET tracer for the evaluation of cardiac beta-adrenergic receptors. The purpose of this study was to evaluate the myocardial kinetics of (11)C-CGP12388 using the perfused rat heart model. METHODS Normal rat hearts were cannulated for retrograde perfusion according to the Langendorff method. Studies were perfor...

(S)-11C-CGP12388 (11C-CGP12388) was recently developed as an in vivo PET tracer for the evaluation of cardiac -adrenergic receptors. The purpose of this study was to evaluate the myocardial kinetics of 11C-CGP12388 using the perfused rat heart model. Methods: Normal rat hearts were cannulated for retrograde perfusion according to the Langendorff method. Studies were performed using constant cor...

The unidirectional gas-flow pattern through the avian lung is thought to result from 'aerodynamic valves'; support for this hypothesis lies mainly in the failure to find any evidence for anatomical valves. During expiration, air flows from the caudal air sacs through the major exchange area of the lung, the paleopulmonic parabronchi, instead of bypassing the lungs via the intrapulmonary bronchu...

Lovastatin therapy is known to induce hepatic low density lipoprotein (LDL) receptor mRNA and LDL receptor activity. Yet, in studies in humans and animals it has been difficult to demonstrate an enhancement of the plasma fractional catabolic rate (FCR) of an injected LDL tracer during lovastatin therapy. One explanation may be that the composition of the LDL tracer may also change during therap...