A 45-year-old woman was found to have a pancreatic tumor by abdominal ultrasound performed for a medical check-up. Abdominal contrast-enhanced computed tomography showed a hypovascular tumor measuring 30 mm in diameter in the pancreatic tail. Endoscopic ultrasound-guided fine needle aspiration was performed. An extragastric growing gastrointestinal stromal tumor was thereby diagnosed preoperati...

Extra-abdominal periosteal desmoid tumors are uncommon nonmetastatic tumors of the extremities with a propensity for local recurrence. Lesions in the distal extremities are rare; a majority of extra-abdominal lesions occur in more proximal portions of the upper and lower extremities. This article reports a patient with an extra-abdominal periosteal desmoid tumor in the toe. A 37-year-old woman ...

Dear Editor, Desmoid tumours are fi brous benign tumours that are often indolent until local symptoms evolve.1 We highlight a rare case of a ruptured intra-abdominal desmoid tumour presenting as acute abdomen. A 58-year-old female presented to our institution with a 1-day history of abdominal pain and vomiting. This was associated with fever, chills and rigors. On examination, the abdomen was t...

Desmoplastic fibromas of bone has been described as a rare, non-metastasizing, locally aggressive, benign lesions that histologically resembles a desmoid tumour of the soft tissue [1,2]. It was initially described by Jaffe in 1958 who highlighted the histological resemblance to aggressive fibromatosis (desmoid tumour) [3]. Since his original description, approximately 150 case reports have been...

BACKGROUND Desmoid tumors associated with familial adenomatous polyposis show variable behavior; about 10% grow relentlessly, resulting in severe morbidity or mortality. Investigations that could identify the minority of desmoid tumors that behave aggressively would allow these tumors to be treated early and spare the majority of patients who have more benign disease from unnecessary interventi...

BACKGROUND Despite the highly selective admission processes utilised by medical schools, a significant cohort of medical students still face academic difficulties and are at a higher risk of delayed graduation or outright dismissal. METHODS This study used survival analysis to identify the non-academic and academic risk factors (and their relative risks) associated with academic difficulty at...

Familial adenomatous polyposis (FAP) is a rare syndrome characterized by the presence of hundreds to thousands of colorectal adenomas and is responsible for less than 1% of all colorectal cancers. The syndrome is also characterized by extra-colorectal features including amongst others upper gastrointestinal tract polyps and desmoid tumors. The syndrome is inherited by an autosomal dominant gene...

Desmoid tumours are rare soft tissue tumours. The a locally invasive monoclonal fibroblastic proliferation leading to variable clinical course. Abnormal functioning of the Wnt/APC/Beta catenin pathway accounts for large proportion desmoid There currently two genetic subtypes: sporadic resulting from somatic CTNNB1 mutations in exon 3 and associated with germline pathogenic variants APC. APC tho...