1. Exchangeable body sodium was measured in deoxycorticosterone acetate (DOCA) -salt-treated rats by whole body y-counting after equilibration with a "Na isotope. 2. The blood pressure of DOCA-salt-treated rats is positively correlated with their exchangeable body sodium. 3. After pithing, the heart rate is significantly lower in DOCA-salt-treated than in control rats: in conscious DOCA-salt-tr...

BACKGROUND Monitoring the properties of dissolved organic carbon (DOC) in soil water is frequently used to evaluate changes in soil quality and to explain shifts in freshwater ecosystem functioning. METHODS Using >700 individual soils (0-15 cm) collected from a 209,331 km(2) area we evaluated the relationship between soil classification (7 major soil types) or vegetation cover (8 dominant cla...

Dissolved organic carbon (DOC) and total dissolved nitrogen (TDN) are generally considered important active biogeochemical pools of total carbon and nitrogen. Many studies have documented the contributions of soil fauna to litter decomposition, but the effects of the soil fauna on labile substances (i.e., DOC and TDN) in litter during early decomposition are not completely clear. Therefore, a f...

Injection of ACTH or cortisone has no effect on the amount of fibrinolysin resulting from the activation of profibrinolysin by peptone. Antifibrinolytic activity of serum is significantly increased by ACTH or cortisone but not by desoxycorticosterone or corticosterone. No increase in anti-fibrinolytic power of serum is produced, however, by the injection of ACTH or cortisone in splenectomized g...

Rats with desoxycorticosterone (DCA) -saline induced hypertension have been shown to exhibit increased susceptibility to experimental pyelonephritis (1, 2). These studies lend support to the hypothesis that various injuries, including nephrosclerosis, predispose to human pyelonephritis and that pyelonephritis is superimposed upon hypertensive disease more frequently than is usually suspected. O...

In a previous report the authors have described the response of young adrenalectomized rats to desoxycorticosterone acetate (DCA) and to cortisone acetate (CA) when maintained on a diet severely restricted in sodium content (1). Daily injections of 2.5 mg. of DCA resulted in progressive weight gain and maintenance of normal blood pressure, while similar doses of CA were accompanied by rapid wei...

Accumulation of granules in the juxtaglomerular cells occurred in rats which were maintained for 5 to 6 weeks on a diet low in sodium, chloride. Cytological evidence suggests that this was probably a storage phase of secretion following a decrease in the rate of liberation of the granules. Administration of DCA (desoxycorticosterone acetate) to salt-deficient rats did not alter this appearance ...

PREVIOUS observations 1 have shown that rats, pretreated with 2-methyl-9a-chlorocortisol (Me-Cl-COL) and an excess of dietary phosphate, develop massive myocardial necroses within a few hours following exposure to various stressor agents. Me-Cl-COL is an artificial synthetic steroid which does not occur in nature; it possesses rather unusual pharmacologic properties in that it is not only extra...