Policy Number: 670 BCBSA Reference Number: 2.04.111 NCD/LCD:  Local Coverage Determination (LCD): MolDX-CDD: Decipher Prostate Cancer Classifier Assay (L35868)  Local Coverage Determination (LCD): MolDX-CDD: ProlarisTM Prostate Cancer Genomic Assay (L35869)  Local Coverage Determination (LCD): MolDX: Prolaris Prostate Cancer Genomic Assay for Men with Favorable Intermediate Risk Disease (L37...

This paper investigates whether the degree of predictability can be explained by existing asset pricing models, and provides two theoretical upper bounds on the R-square of the regression of stock returns on predictors for given classes of models of interest. Empirically, we find that the predictive R-square is significantly larger than the upper bounds permitted by well known asset pricing mod...

Results for the application of an adaptive background model to the problem of detecting changes on a combs surface are reported. It is demonstrated that the combined search for uncapped brood cells in the current image and the background image increases the overall detection rate of the system.

We herein describe a procedure that allows for simultaneous genotyping of six loss-of-function mutations in the bovine myostatin gene associated with the double-muscling phenotype. The proposed method relies on a multiplex oligonucleotide ligation assay and detection of the fluorescently labelled products using automatic sequencers.

Hand-crafted approaches to content determination are expensive to port to new domains. Machine-learned approaches, on the other hand, tend to be limited to relatively simple selection of items from data sets. We observe that in time series domains, textual descriptions often aggregate a series of events into a compact description. We present a simple technique for automatically determining sequ...

The wide availability of hardwired Z-buffer has sparked an explosion in the number of applications of the algorithm whose origins lie in hidden surface elimination. This paper presents a much-needed survey of key applications of the Z-buffer from the fields of rendering, modelling and vision in a common notation in order to help users make better use of this resource.

In this paper we describe a two-stage model for content determination in systems that summarise time series data. The first stage involves building a qualitative overview of the data set, and the second involves using this overview, together with the actual data, to produce summaries of the timeseries data. This model is based on our observations of how human experts summarise time-series data.

The identification of complex disease susceptibility loci has been accelerated considerably by advances in high-throughput genotyping technologies, improved insight into correlation patterns of common variants and the availability of large-scale sample sets. Linkage scans and small-scale candidate gene studies have now given way to genome-wide association scans. In this review, we summarize ins...