Quality carcass and non-carcass are two inseparable components that result from slaughtering animals with high economic value. The aims study is effect of polimorfisme DGAT1 gene on hot cold carcass, neck traits in Indonesia sheep. A total 50 rams used this were collected 10 Barbados Cross Sheep (BCS), Compass Agrinac (CAS), 15 Javanese Thin-Tailed (JTTS), Jonggol (JS). sheep slaughtered at 10-...

Abstract Background Acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) catalyzes the final step in triglyceride (TG) synthesis and is highly expressed enterocytes (EC). DGAT1 deficiency (DGAT1D) a rare autosomal recessive protein losing enteropathy (PLE) classified as congenital diarrheal disorder (CDD). Presumably, fat ingestion causes accumulation of substrates within EC causing lipotoxicity-i...

Arabidopsis seeds store triacylglycerol (TAG) as the major carbon reserve, which is used to support postgerminative seedling growth. Diacylglycerol acyltransferase (DGAT) catalyzes the final step in TAG synthesis, and two isoforms of DGAT have previously been identified in Arabidopsis. It has been shown that DGAT1 plays an important role in seed development because Arabidopsis with mutations at...

Genes in the sterol regulatory element-binding protein-1 (SREBP1) pathway play a central role in regulation of milk fat synthesis, especially the de-novo synthesis of saturated fatty acids. SCD, a SREBP-responsive gene, is the key enzyme in the synthesis of monounsaturated fatty acids in the mammary gland. In the present study, we discovered SNP in candidate genes associated with this signallin...

The purpose of this study was to compare the expression profiles of drug-metabolizing enzymes in the intestine of mouse, rat and human. Total RNA was isolated from the duodenum and the mRNA expression was measured using Affymetrix GeneChip oligonucleotide arrays. Detected genes from the intestine of mouse, rat and human were ca. 60% of 22690 sequences, 40% of 8739 and 47% of 12559, respectively...

Algae have recently gained attention as a potential source for biodiesel; however, much is still unknown about the biological triggers that cause the production of triacylglycerols. We used RNA-Seq as a tool for discovering genes responsible for triacylglycerol (TAG) production in Chlamydomonas and for the regulatory components that activate the pathway. Three genes encoding acyltransferases, D...