In examining the pathophysiology underlying the development of hypertension in diabetes mellitus, it is important to draw clear distinctions between Type I and Type II diabetes. In patients with Type I diabetes, with a peak onset of disease early in the second decade of life, hypertension clearly represents the sequelae to the development of substantial renal lesions, especially in the glomerul...

We investigated serum concentration of C-reactive protein (CRP) and measures of adiposity in 30 patients with type 2 diabetes mellitus (15 male, 15 female) and 30 age and sex-matched apparently healthy subjects. CRP concentration was determined by laser nephelometry (BN II Analyzer) and CardioPhase high-sensitivity CRP (DADE BEHRING) was used as reagent which consists of polystyrene particles c...

patients with type 1 diabetes mellitus have a high prevalence of coeliac disease, symptoms of which are often mild, atypical, or absent. untreated coeliac disease is associated with an increased risk of malignancy, particularly of lymphoma. therefore, we report a 9-year-old girl with coeliac disease, diabetes type 1 and selective iga deficiency. a 9-year-old female patient presented in august 2...

Visual evoked potentials (VEPs) were assessed in 50 adult type I (insulin-dependent) and 19 type II (noninsulin-dependent) diabetes mellitus patients and in 54 controls. P100 wave latency was significantly longer in diabetic patients (P less than .001). Twenty-eight percent of diabetic patients had P100 wave latencies above the normal range. There was no correlation between P100 latency and typ...

Health literacy is the first step to self-management of type II diabetes mellitus, of which physical activity is the least compliant behavior. However, no reviews have summarized the effect and the process of interventions of health literacy oriented programs on physical activity behavior among middle aged and older adults with type II diabetes mellitus. This article is the first to examine the...

recent studies suggested the role of white blood cells (wbcs) in the pathogenesis and complications of type 2 diabetes. increased wbc counts predict mortality in patients with chronic kidney disease (ckd). in this study alterations in wbc subpopulations in diabetic patients with non-dialysis dependent ckd are investigated. this was a cross-sectional study  on 376 participants, including   272 d...

docosahexaenoic acid (dha), as an omega-3 fatty acid, in a natural ligand of peroxisome proliferator-activated receptors (ppars). regarding the combinative effects of nutrigenomics and nutrigenetics and due to the lack of in vivo studies conducted using natural ligands of ppars, we aimed to evaluate the effects of dha supplementation on vascular function, telomerase activity, and pparγ-lxrα-abc...

patients and methods this prospective cohort study was performed on 90 diabetic type 2 patients with microalbuminuria, who were selected according to the consecutive sample selection method during 6 years. data were collected through regular and systematic measurements of serum albumin as the response variable and body mass index, systolic and diastolic blood pressure, the duration of diabetes,...

considering that mapk (mitogen- activated protein kinase) signaling pathway has an important role in the progression of inflammatory cytokine secretion in type 2 diabetes mellitus (t2dm), we have recently investigated the reported genetic polymorphism from genome wide association study in map3k1 (mitogen-activated protein kinase kinase kinase 1) in diabetes as an important member of mapk signal...