PURPOSE To evaluate the patient characteristics and fundus findings of patients with type II diabetes presenting with diabetic papillopathy. METHODS The authors retrospectively reviewed the medical records of 3,235 patients with diabetes followed in their institution since 1986 and identified the patients with unilateral or bilateral transient disk swelling and without significant deteriorati...

Chronic renal failure affects every organ system including eye. The aim of this study is to conduct thorough ocular examination in the patients of chronic renal failure and to analyze the findings. 119 cases were collected from Nephrology unit of Tribhuvan University Teaching Hospital between 1st June 2002 to 15th December 2003. This was a cross sectional, descriptive type of study. Sampling te...

Purpose To compare the diagnostic properties of a nonmydriatic 200° ultra-widefield scanning laser ophthalmoscope (SLO) versus onsite mydriatic ophthalmologic examination for diabetic retinopathy. Methods A consecutive series of 51 eyes of 51 patients with different levels of diabetic retinopathy (DR) was examined. Grading of diabetic retinopathy and macular edema obtained on stereoscopic dilat...

PURPOSE To evaluate the effect of intravitreal triamcinolone acetonide in patients with diffuse diabetic macular edema on the visual acuity and intraocular pressure. To report the potential adverse events and to analyze the potential relationship between age and visual acuity and intraocular pressure variability. METHODS This clinical controlled study included 14 patients (28 eyes), 14 of the...

In a retrospective study we have examined all diabetics (66 operated eyes) and an equal number of non-diabetic matched controls who underwent extracapsular cataract extracation (ECCE) with intraocular lens (IOL) implantation over a two-year period ending in December 1987. Of the diabetic patients' 76% eyes improved by at least two lines of Snellen acuity postoperatively. Of these patients 68% e...

PURPOSE Diabetic retinopathy is the leading cause of blindness among working-age adults in most developed countries. It affects eyes bilaterally and is generally believed to be symmetrical, yet there are few studies evaluating the symmetry of diabetic retinopathy. The purpose of the present study was to evaluate the symmetry of the amount of peripheral retinal ischemia in patients with diabetic...

PURPOSE To evaluate the effect of diabetes on rhodopsin regeneration in the excised mouse eye. METHODS A superfused excised mouse eye preparation that exhibits rhodopsin regeneration after moderate bleaches and that is responsive to the composition of the perfusate was used. Diabetes was induced in albino mice (BALB/c) with the diabetogenic agent streptozotocin. Absorption spectrophotometry o...

PURPOSE To describe the pathoanatomy of diabetic choroidopathy (DC) in pre-diagnosed diabetic retinopathy (DR) cases and to provide angiographic and optical evidence for DC using indocyanine green angiography (ICGA) and enhanced depth imaging spectral-domain optical coherence tomography (EDI SD-OCT). METHODS A retrospective analysis of 80 eyes from 40 DR patients was conducted. In Group One, ...

Purpose: To evaluate the efficacy of computer algorithms in the detection and grading of retinopathy derived from screening of diabetic photographs. Methods: Screening fundus photographs (5 per eye) taken with a mydriatic camera in a general ophthalmology clinic for 52 sequential diabetic patients were graded by a general ophthalmologist and a retina specialist and compared with computer gradin...

Purpose: To evaluate efficacy, safety, and causes of vision loss among 813 patients (1,392 eyes) with moderately severe to very severe nonproliferative diabetic retinopathy from the Protein Kinase C b Inhibitor-Diabetic Retinopathy Study and Protein Kinase C b Inhibitor-Diabetic Retinopathy Study 2 ruboxistaurin (RBX) protein kinase C b inhibitor trials. Methods: Patients in these 3-year, rando...