Carcinoid heart disease is a rare cause of heart failure with or without right valvular heart impairments. In this study, we showed a case of carcinoid tumour with hepatic metastases inducing carcinoid heart disease. Neuroendocrine heart involvement happens for severe tricuspid valve insufficiency and plaques on right ventricular (RV) walls produced by a release of serotonin (5-HT). A patient a...

Adrenal insufficiency is a life-threatening disorder which must be treated with glucocorticoid replacement and needs permanent dose adjustment during patient's different somatic situations. Insufficient glucocorticoid doses result in adrenal crisis and must be treated with intravenous hydrocortisone. The patient was known with Adrenal insufficiency and was treated optimally with fludrocortisone...

Abstract Clinical case We describe a of 62–y–old man, affected by hypertension, insulin–dependent diabetes mellitus, advanced liver cirrhosis. After screeing, the patient was listed for transplantation. On September 2022, admitted to our Emergency Room due HF in class NYHA III. The transthoracic echocardiogram showed severe aortic regurgitation with mobile vegetations, largest which is more tha...

BACKGROUND The clinical pattern and long-term course of chronic inferior vena cava (IVC) obstructions are variable and depend on the underlying cause, the segment involved, and the extension of secondary thrombosis. Pertinent data on IVC obstructions in well-defined series of patients are lacking. We report the sequelae of chronic IVC obstructions in the hepatic segment in 11 consecutive patien...

Abstract: Cancer patients experience weight loss for a variety of reasons, commencing with the tumor's metabolism (Warburg effect) and proceeding via cachexia to loss of appetite. In pancreatic cancer, several other factors are involved, including a loss of appetite with a particular aversion to meat and the incapacity of the pancreatic gland to function normally when a tumor is present in the ...

Acute aortic valvular insufficiency was induced in open chest dogs by employing a special intravascular cannula, or by rupturing an aortic valve leaflet. Phasic and mean coronary flow were assessed in some animals, while in others data were obtained on arterial and coronary sinus blood lactate, pyruvate, P(O2), P(CO2), and pH, and on myocardial tissue lactate, pyruvate, and water content in the...

Results Our sample included 42 patients with juvenile idiopathic arthritis (JIA, mean age at evaluation 13.9 ± 7.9 years, mean disease duration was 6.9 ± 7.6 years, Male/Female ratio:10/32). Among them, 27 (64.3%) were oligoarthritis, 13 (30.9%) polyarthritis, 1 (2.4%) systemic arthritis and 1 (2.4%) psoriasic arthritis. Uveitis were present in 6 patients. Only 5 patients had clinical and labor...