NGS is a powerful tool for the diagnostics of inherited diseases. A number of studies devoted to the development and validation of targeted NGS panels are published. Here we present not only development and validation of an assay, but report our experience on introduction of a new approach into the real clinical practice. The assay is intended for the diagnostics of frequent newborn inherited d...

background handheld computers play an increasing role in improving healthcare services by making the information available at the point of care. there is not enough evidence regarding the usage of handheld computers by healthcare professionals in developing countries. objectives this study investigated the benefits and barriers of using handheld computers in clinical practice in a developing co...

Differential cross sections (DCSs) for elastic scattering of electrons from alanine, have been measured using a crossed beam system for incident energies between 20 eV and 80 eV and scattering angles from 10$^{o}$ to 150$^{o}$. The experimental data were placed upon an absolute scale by normalisation to calculated absolute integral cross sections obtained using the corrected independent atom me...

objective: to develop decision-support tools to identify patients experiencing sudden cardiac arrest (sca). methods: eighty calls related to sca were content analyzed, and the contextual patterns that emerged were organized into a checklist. two researchers independently analyzed the recorded calls and compared their findings. eighteen dispatchers scored 20 cases (which included sca and non-sca...

BACKGROUND Health technology assessments (HTAs) are increasingly used to inform coverage, access, and utilization of medical technologies including molecular diagnostics (MDx). Although MDx are used to screen patients and inform disease management and treatment decisions, there is no uniform approach to their evaluation by HTA organizations. OBJECTIVES The International Society for Pharmacoec...

BACKGROUND The lack of adequate information about fever in low-resource settings, its unreliable self-assessment, and poor diagnostic practices may result in delayed care and under-or-overdiagnosis of diseases such as malaria. The mismatches of existing fever thermometers in the context of use imply that the diagnostic tools and connected services need to be studied further to address the chall...

We report results from a joint theoretical and experimental investigation into electron scattering from the important organic species phenol (C6H5OH). Specifically, differential cross sections (DCSs) have been measured and calculated for the electron-impact excitation of the electronic states of C6H5OH. The measurements were carried out at energies in the range 15-40 eV, and for scattered-elect...

This paper present the work on Cognitive Radio Networks (CRN) to improve the spectrum sensing performance. By using distributed coordinated spectrum sensing all the Secondary Users (SUs) are grouped into optimum number of clusters, selection of each cluster is based on the priority of predefined Cluster Heads(CHs) among secondary users. All the CHs collects the source information from the remai...