نتایج جستجو برای: differentiated neuroendocrine carcinoma

تعداد نتایج: 459233  

2017
Nathanaëlle Montanier Juliette Joubert-Zakeyh Caroline Pétorin Pierre François Montoriol Salwan Maqdasy Antony Kelly

RATIONALE Pancreatic neuroendocrine tumors (pNET) are rare slowly growing tumors with a high metastatic potential. Peptide receptor radionuclide therapy (PRRT) with radiolabeled analogues has been developed as a new tool for the management of metastatic well-differentiated (grade 1 and 2) neuroendocrine tumors expressing somatostatin receptor (SSTR2). Chemotherapy is the mainstay in the managem...

Journal: :Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia 2005
Yoshito Yamada Akira Iyoda Makoto Suzuki Teruaki Mizobuchi Masayuki Baba Kenzo Hiroshima Hidemi Ohwada Takehiko Fujisawa

We report a rare case of double primary lung carcinoma including large cell neuroendocrine carcinoma (LCNEC). A 67-year-old man underwent an annual medical checkup in 2000, pulmonary carcinoma was strongly suspected by sputum cytology and radiological images. Preoperative diagnosis was double primary lung carcinoma with a squamous cell carcinoma in the right lower lobe and non-small cell carcin...

2012
Mee-Yon Cho Joon Mee Kim Jin Hee Sohn Mi-Jung Kim Kyoung-Mee Kim Woo Ho Kim Hyunki Kim Myeong-Cherl Kook Do Youn Park Jae Hyuk Lee HeeKyung Chang Eun Sun Jung Hee Kyung Kim So-Young Jin Joon Hyuk Choi Mi Jin Gu Sujin Kim Mi Seon Kang Chang Ho Cho Moon-Il Park Yun Kyung Kang Youn Wha Kim Sun Och Yoon Han Ik Bae Mee Joo Woo Sung Moon Dae Young Kang Sei Jin Chang

PURPOSE As a result of various independently proposed nomenclatures and classifications, there is confusion in the diagnosis and prediction of biological behavior of gastroenteropancreatic neuroendocrine tumors (GEP-NETs). A comprehensive nationwide study is needed in order to understand the biological characteristics of GEP-NETs in Korea. MATERIALS AND METHODS We collected 4,951 pathology re...

Journal: :World Journal of Surgical Oncology 2008
Roberto Gedaly Hoonbae Jeon Thomas D Johnston Patrick P McHugh Randall G Rowland Dinesh Ranjan

BACKGROUND Carcinoid tumors are characteristically low grade malignant neoplasms with neuroendocrine differentiation that arise in various body sites, most commonly the lung and gastrointestinal tract, but less frequently the kidneys, breasts, ovaries, testes, prostate and other locations. We report a case of a carcinoid of renal origin with synchronous single liver metastases on radiological s...

Journal: :Environmental Health Perspectives 1998
P. S. Hasleton S. Gomm V. Blair N. Thatcher

were the clinical variables affecting survival. The histological variables related to survival were; mitotic count, necrosis, nuclear pleomorphism, vascular and lymphatic permeation and an undifferentiated growth pattern. All these features could be detected with routine histological stains, whereas immunocytochemical methods for demonstrating neuron specific enolase were of no help in assessin...

2011
Yo Na Kim Ho Sung Park Kyu Yun Jang Woo Sung Moon Dong Geun Lee Ho Lee Min Ro Lee Kyung Ryoul Kim

Large cell neuroendocrine carcinomas of the colon are rare and represent only a small percentage of all colonic endocrine tumors. Here, we report a case of a colonic large cell neuroendocrine carcinomas concurrent with a colonic adenocarcinoma. A 70-year-old man presented with acute abdominal pain. A spiral computed tomography scan of the abdomen revealed eccentric wall thickening on the ascend...

Journal: :Annals of oncology : official journal of the European Society for Medical Oncology 2011
T Shoji H Fushimi S Takeda Y Tanio

Large-cell neuroendocrine carcinoma (LCNEC) of the thymus is a rare aggressive neoplasm. Its precise prognosis has not yet been determined. The recently published European Society of Medical Oncology (ESMO) clinical practice guidelines for neuroendocrine bronchial and thymic tumors [1] defined LCNEC and small-cell carcinoma (SCC) of the thymus as high-grade thymic carcinoids with a 5-year survi...

2017
Hiromi Kanno-Okada Tomoko Mitsuhashi Katsuhiro Mabe Tadakazu Shimoda Yoshihiro Matsuno

BACKGROUND Although adenocarcinomas showing neuroendocrine differentiation or those mixed with high-grade neuroendocrine carcinoma (NEC) are sometimes encountered, composite tumors comprising neuroendocrine tumor (NET) Grade 1 and adenocarcinoma are exceedingly rare. CASE PRESENTATION A 64-year-old male presented after testing positive for fecal occult blood at a medical check-up. A biopsy de...

2016
Javier De Luca-Johnson Maryam Zenali

We report a case of mixed adenoneuroendocrine carcinoma (MANEC) of stomach with tubular adenoma and well-differentiated neuroendocrine tumor (WD-NET) in the primary tumor in the stomach giving rise to biphenotypic regional nodal metastases. A 35-year-old woman with abdominal pain was found to have a 1.8-cm gastric lesion, diagnosed as WD-NET (intermediate grade) on the biopsy. The resection spe...

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