In exocrine pancreatic insufficiency (EPI) there is insufficient production or secretion of digestive enzymes by the pancreas with associated maldigestion. Usually multiple enzymes need to be affected to show clinical disease, although there is one report of a patient with a lipase-only defect. Since lipase is the rate-limiting enzyme in pancreatic digestion, deficiency in just that single enzy...

In the rat, under constant illumination, the activities of the digestive enzyme sucrase and the absorptive transport system for glucose follow circadian rhythms on ad lib. and controlled feeding regimens. In response to controlled feeding, (1400-1800 h or 0200-0600 h, EST), both rhythms shift with time and the general level of activities are enhanced. Sucrase activity peaks before feeding and t...

The aim of this paper is to provide explanations of how dietary phospholipid (PL) globally improves fish larval development, including growth and survival, digestive functions and skeletal development, and to propose optimal PL levels and sources in fish larval diets. Dietary incorporation of 8–12% PL related to dry matter (d.m.) promotes growth and enhanced survival in various species. Marine ...

This seminar text reviews various forms of enzyme supplementation used clinically in digestive and absorption disorders. Enzyme supplementation plays an integral role in the management of various digestive disorders, particularly with regard to exocrine pancreatic insufficiency. However, application of enzymes may also be beneficial for other conditions associated with poor digestion including ...