Based on partially-coherent digital in-line holography, we report a field-portable microscope that can render lensfree colour images over a wide field-of-view of e.g., >20 mm(2). This computational holographic microscope weighs less than 145 grams with dimensions smaller than 17×6×5 cm, making it especially suitable for field settings and point-of-care use. In this lensfree imaging design, we m...

BACKGROUND Myringotomy with tube insertion can be challenging for junior Otolaryngology residents as it is one of the first microscopic procedures they encounter. The Western myringotomy simulator was developed to allow trainees to practice microscope positioning, myringotomy, and tube placement. This virtual-reality simulator is viewed in stereoscopic 3D, and a haptic device is used to manipul...

We present a platform for designing and executing studies that compare pathologists interpreting histopathology of whole slide images (WSIs) on a computer display to pathologists interpreting glass slides on an optical microscope. eeDAP is an evaluation environment for digital and analog pathology. The key element in eeDAP is the registration of the WSI to the glass slide. Registration is accom...

In this work we present an automatic algorithm for detection of mycobacterium tuberculosis from stained sputum smear images applying a novel method of tubeness filtering in conjunction with Otsu thresholding and connected component analysis. This eliminates human effort and measurement error from the detection of the bacteria, which normally requires a lab technician or pathologist to load a gl...

This corrects the article DOI: 10.1038/ncomms13040.

objective: in previous studies it has been emphasized that the site of morphine action may be either in the embryo or the placenta. in the present study, we attempt to identify the site of morphine action on the fetal section of wistar rat placenta by using c14-morphine. materials and methods: in this study (experimental), female wistar rats (weights: 170-200 g) were mated with male rats and th...

Digital imaging in cytopathology can be defined as a series of procedures, those contributing to the quality of the displayed on the computer monitor final image. The procedures include sample preparation and staining, optical image formation by the microscope and afterwards the digital image sampling by the camera sensor; which means digital image post-processing and compression, transmission ...