We tested the hypothesis that age-related endothelial dysfunction in rat soleus muscle feed arteries (SFA) is mediated in part by NAD(P)H oxidase-derived reactive oxygen species (ROS). SFA from young (4 mo) and old (24 mo) Fischer 344 rats were isolated and cannulated for examination of vasodilator responses to flow and acetylcholine (ACh) in the absence or presence of a superoxide anion (O(2)(...

Hyperhomocysteinemia (HHcy) impairs endothelium-dependent vasodilation by increasing reactive oxygen species, thereby reducing nitric oxide (NO.) bioavailability. It is unclear whether reduced expression or function of the enzyme that produces NO., endothelial nitric oxide synthase (eNOS), also contributes. It is also unclear whether resistance vessels that utilize both NO.and non-NO.vasodilato...

Upper and lower probabilities may become uniformly less precise after conditioning. We call this dilation. We review some results about dilation, present some examples and explore the effect of Bayesian updating. Also, we show a connection between dilation and nonconglomerability. Finally, we consider the implications of this phenomenon. AMS Subject Classifications: Primary 62F15; Secondary 62F35

On-line audio dilation is a technique that time stretches, or slows down the tempo of audio signals as they are generated. This paper presents an on-line dilation technique and our ongoing research to assess the effects of audio dilation on speech communication using an interactive DIAPIX problem solving task.

Because methionine enkephalin contributes to and dynorphin opposes dilation during a 10-min hypoxic exposure, opioids modulate pial artery dilation to this stimulus. However, such modulation may be dependent on the duration of hypoxia. The present study was designed to characterize the modulation of hypoxic pial dilation by opioids as a function of stimulus duration in newborn pigs equipped wit...

OBJECTIVES The purpose of the study was to evaluate the relationship between elevated lung/heart ratio (LHR) and transient ischemic dilation (TID) after stress thallium-201 myocardial perfusion imaging and to provide further insight into the mechanism of cavity dilation. BACKGROUND Because both LHR and TID have been identified as adjunctive markers of severe coronary disease they should be fo...

BACKGROUND AND OBJECTIVE Increased air pollutants correlate with increased incidence of cardiovascular disease potentially due to vascular dysfunction. We have reported that acute diesel engine exhaust (DE) exposure enhances vasoconstriction and diminishes acetylcholine (ACh)-induced dilation in coronary arteries in a nitric oxide synthase (NOS)-dependent manner. We hypothesize that acute DE in...

Objective: This study aims to evaluate the safety and clinical efficacy of warfarin anticoagulation after small balloon pre-dilation for treating Budd-Chiari syndrome (BCS) complicated with inferior vena cava (IVC) thrombosis. Methods: This prospective study analyzed the consecutive clinical data of 53 patients with BCS complicated with IVC thrombosis, who were admitted in our hospital from Jan...

Vertebroplasty is often used to treat osteoporotic vertebral compression fractures (OVCF). The number of affected vertebrae can be reduced to a certain extent by some reduction methods including hyperextension and balloon dilation. There have been only a few studies on the effectiveness of vertebroplasty combined with hyperextension or balloon dilation. We collected data of 216 OVCF patients wh...