Accurate segregation of chromosomes during cell division is essential. The Dam1 complex binds kinetochores to microtubules and its oligomerization is required to form strong attachments. It is a key target of Aurora B kinase, which destabilizes erroneous attachments allowing subsequent correction. Understanding the roles and regulation of the Dam1 complex requires structural information. Here w...

The determination of creatinine by HPLC was performed by direct injection of serum onto the column, and after ultrafiltration of the sample, and the results were compared. A modified weak cation exchange column was used for HPLC. This eliminates the protein displacement effect and the Gibbs-Donnan effect, thus permitting a rapid direct analysis. Three of the four ultrafiltration methods gave al...

STUDY DESIGN A retrospective, one center, institutional review board approved study. OBJECTIVE Two methods of operative treatments were compared in order to evaluate whether a two-stage approach is justified for correction of bigger idiopathic scoliosis curves. Two stage surgery, combined anterior approach in first operation and posterior instrumentation and correction in the second operation...

BACKGROUND Effective connectivity can be explored using direct electrical stimulations in patients suffering from drug-resistant focal epilepsies and investigated with intracranial electrodes. Responses to brief electrical pulses mimic the physiological propagation of signals and manifest as cortico-cortical evoked potentials (CCEP). The first CCEP component is believed to reflect direct connec...

An instrument has been developed by which the bilirubin concentration in serum is determined spectrophotometrically.A readingof the difference in absorbanceat450me and 540 m is obtained. The presenceof hemoglobinor turbidity is corrected for, so that the differential absorbancereading, multiplied by a calibration factor, gives the correct bilirubin concentration. Comparisonswith analysesusinga ...

A new method to fit specific types of conics to scattered data points is introduced. Direct, specific fitting of ellipses and hyperbolae is achieved by imposing a quadratic constraint on the conic coefficients, whereby an improved partitioning of the design matrix is devised so as to improve computational efficiency and numerical stability by eliminating redundant aspects of the fitting procedu...

Introduction Although the first-pass myocardial perfusion MRI has proven its effectiveness in the diagnosis of ischemic heart disease, this technique is still not routinely used. Certain technical difficulties prevent perfusion MRI from being added into the clinical workflow, including complex cardiac motion, limited imaging time, and B1-field inhomogeneity caused by non-uniform characteristics...

Correction of nonlinear and frequency dependent distortion in a 3.3 GHz, 16-element digital phased array is demonstrated using the memory polynomial model from [4] and a weighted least-squares approach. Practical results are given, showing that a single solution of the system can correct distortion from data sets across the whole operational bandwidth of the array. Subsequent analysis of perfor...

Step -scan transient F ourier tran sform infrared (FT-IR ) d ifference sp ectra are often m easured in an ac-coup led con ® guration . The resu lting differential intensity sp ectra con tain both posit ive and negative bands. This condition poses problem s for d irect phase correction by the standard M ertz and Form an methods. Restricting th e calculated phase angle to the range [ 2 p /2, p /2...

Holistic local visual homing based on warping of panoramic images relies some simplifying assumptions about the and environment to make problem more tractable. One these is that are captured flat ground without tilt. While this might be true in environments, it poses a for wider real-world application warping. An extension framework proposed where tilt-corrected used as inputs. The method combi...