BACKGROUND On 30 September 2009, a 7.6 magnitude earthquake severely hit the coast of Padang city in West Sumatra, Indonesia leaving about 1,117 people dead and injuring another 3,515. Health consequences such as physical injury, co-morbidity, disability and quality of life over time are seldom reported among survivors after earthquakes. OBJECTIVES To investigate the associations between inju...

IMPORTANCE Little is known about functional trajectories of older persons in the year before and after admission to the intensive care unit (ICU) or how pre-ICU functional trajectories affect post-ICU functional trajectories and death. OBJECTIVES To characterize functional trajectories in the year before and after ICU admission and to evaluate the associations among pre-ICU functional traject...

A model was developed to estimate the medical costs and effectiveness outcomes of three antipsychotic treatments (olanzapine, haloperidol, and risperidone) for patients with schizophrenia. A decision analytic Markov model was used to determine the cost-effectiveness of treatments and outcomes that patients treated for schizophrenia may experience over a 5-year period. Model parameter estimates ...

validity of disability adjusted life years The value of DALY life: problems with ethics and service Email alerting the top left of the article Receive free email alerts when new articles cite this article-sign up in the box at

BACKGROUND Disability-Adjusted Life Years (DALYs) have the advantage that effects on total health instead of on a specific disease incidence or mortality can be estimated. Our aim was to address several methodological points related to the computation of DALYs at an individual level in a follow-up study. METHODS DALYs were computed for 33,507 men and women aged 20-70 years when participating ...

OBJECTIVE To examine the association between optimal adherence to the first-generation injectable immunomodulatory drugs (IMDs) for multiple sclerosis (MS) and subsequent disability accumulation. METHODS We accessed prospectively collected linked clinical and administrative health data from British Columbia, Canada. Subjects with MS treated with a first-generation injectable IMD at an MS clin...

BACKGROUND Developing effective methods for measuring the health impact of social franchising programs is vital for demonstrating the value of this innovative service delivery model, particularly given its rapid expansion worldwide. Currently, these programs define success through patient volume and number of outlets, widely acknowledged as poor reflections of true program impact. An existing m...

background: economic evaluation includes evaluation of costs and benefits of screening. one of the economic evaluation methods is cost-effectiveness analysis. the aim of this study was cost-effectiveness analysis of type 2 diabetes screening in shiraz, iran.   methods: the target population of this cross-sectional study consisted of all shiraz population over 30 years old. a total of 171067 per...