BACKGROUND Our study investigated 2 common single-nucleotide polymorphisms (SNPs) of vascular endothelial growth factor (VEGF) for their influences on serum VEGF levels, disease activity, and synovial lesions in rheumatoid arthritis (RA). MATERIAL/METHODS Clinical information and venous blood samples were collected from 98 RA patients and 100 healthy controls. Genotyping on samples from the s...

OBJECTIVES The provisional ACR/European League Against Rheumatism (EULAR) definition of remission in RA requires a score of ≤1 on the patient global assessment (PGA, 0-10 scale). We explored the relation between the PGA criterion and the patient's clinical disease state in an observational dataset. METHODS Data of 512 newly diagnosed RA patients of the Dutch Rheumatoid Arthritis Monitoring (D...

A case of Uthiravathasronitham (Rheumatoid arthritis) had been treated with a classical Siddha preparation Rasa chenduram (100mg) along Thirikadugu choornam (1 gm) for 3 weeks and Pinda thailam as an external application. The patient condition has assessed by validated simplified disease activity measurement tool Rheumatoid arthritis Disease score (DAS) 28 joints formula using Erythrocyte sedim...

Objectives: To determine and compare the impact of rheumatoid arthritis (RA), ankylosing spondylitis (AS), and psoriasis on work productivity, to calculate the productivity costs (PC), and to map out factors that influence (functional status and disease activity) work productivity. Methods: The Work Productivity and Activity Impairment questionnaire was used to evaluate productivity losses of p...

In order to investigate the predictive factors related to clinical efficacy and radiographic progression at 24 weeks by looking at the serum levels of tumor necrosis factor (TNF)-α and interleukin (IL)-6 including baseline characteristics in patients with rheumatoid arthritis (RA) treated with golimumab, serum concentrations of TNF-α and IL-6 were analyzed every 4 weeks up to 24 weeks in 47 pat...

OBJECTIVE The aim of the Patient/Physician Reported Efficacy Determination In Clinical Practice Trial (PREDICT; ClinicalTrials identifier NCT01255761) was to compare the patient-reported Routine Assessment of Patient Index Data 3 (RAPID-3) instrument with the investigator-based Clinical Disease Activity Index (CDAI) for assessing certolizumab pegol (CZP) treatment response in rheumatoid arthrit...

Background: Rheumatoid arthritis (RA) patients have a greater prevalence of anxiety and depression. Proinflammatory cytokines are elevated in RA. We aim to evaluate the association between systemic inflammation RA Methods: There were 31 patients, 16 with active disease activity 15 remission state; they assessed using Hospital Anxiety Depression Scale for Disease Activity Score 28 joints (DAS28)...