In this study, liquid-liquid extraction process in a Kuhni extraction column was modeled and simulated. A non-equilibrium dynamic model was developed for modeling liquid-liquid extraction processes based on a rate-based model. The model equations are inclusive of partial and ordinary differential equations which were discretized in column height direction. The population balance model was used ...

Hot Melt Extrusion (HME) is well known process for the Plastic Industries but it is well accepted by the pharmaceutical industries for the last three decays. With the use of HME we can increase solubility and bio-availability of the API. HME has proven to be a robust method of producing numerous drug delivery systems like modified, controlled and targeted drug delivery systems.HME is a solvent ...

The aim of this study was to better understand the underlying drug release mechanisms in poly(lactic-co-glycolic acid) (PLGA) microparticles which is dispersed form tiny particles (“monolithic dispersions”). Differently sized diprophylline-loaded were prepared using a solid-in-oil-in-water solvent extraction/evaporation technique. characterized before and after exposure phosphate buffer pH 7.4 ...

oxime extractants 3-tert-butyl-2-hydroxy-5-methyl benzaldehyde oxime (hl1) and 3-tert-butyl-2-hydroxy-5-methoxy benzaldehyde oxime (hl2) were synthesized and characterized by conventional spectroscopic methods. suitable lipophilic nature of the prepared extractants allowed examining the ability of these molecules for extraction-separation of copper from its mixture with normally associated meta...

gallium extraction from jajarm bayer process liquor (jajarm, iran) was investigated using microemulsions. also the behavior of aluminum was studied as an impurity. kelex100 (4-ethyl, 1-methyl, 7-octyl, 8-hydroxyquinoleine), iso-decanol and n-butanol, and kerosene were used as the surfactant, co-surfactant, and oil phase, respectively. ternary phase diagrams were produced using various co-surfac...

tea and sesame seed oils extracted by different methods (including supercritical fluid extraction (sfe), at a pressure of 350 atm, a temperature of 60oc, a static extraction time of 20 minutes, a dynamic extraction time of 30 minutes and 150 g kg-1 of ethanol as a modifier). solvent (se) and ultrasound-assisted solvent extraction (ue)), as natural anti-oxidants, were evaluated during 15 days st...

background & aim: essential oils are isolated from different sections of plants such as flowers, seeds, leaves, stems and roots. essential oils are applied extensively in producing of perfumes, cosmetics, foods, beverages and confectioneries and as ingredients of disinfectants and insecticides. experimental: essential oil are obtained by several isolation methods, such as hydrodistillation ...

A new, sensitive and fast dispersive liquid-liquid microextraction (DLLME) coupled with micro-solid phase extraction (μ-SPE) was developed for determination of zearalenone (ZEN) in wheat samples. The DLLME was performed using acetonitrile/water (80:20 v/v) as the disperser solvent and 1-octanol as the extracting solvent.  The acetonitrile/water (80:20 v/v) solvent was also used to extract ZEN f...

In this work, an environmentally friendly sample pre-treatment method, Ultrasound Assisted Surfactant Enhanced Emulsification Microextraction (UASEME) followed with spectrofluorimetry was performed for determination of oxadiazon residues in water samples. After the determination of the most suitable extraction solvent and its volume, other parameters such as type and concentration of surfac...

Three organic ionophores (2-4) based on the p-tert-butylthiacalix[4]arene backbone, blocked in the 1,3-alternate conformation, bearing two pyridyl coordinating moieties (ortho for 2, meta for 3 and para for 4), have been synthesized and characterized in the solid state. The solvent extraction experiments with the metal ions showed that the ability of these derivatives to complex with Ag(+) appe...